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description:Translational Medicine Communications is an interdisciplinary forum for all scientifically valid research from across translational medicine. We are committed ...
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Featured article: Emerging roles of C1Q tumor necrosis factor-related proteins in metabolic diseases

Obesity and insulin resistance are key elements of the metabolic syndrome. C1Q Tumor necrosis factor-related proteins (CTRPs) have recently emerged as important regulators of metabolism as a core component in the interrelationship between insulin resistance, adiposity and inflammation.


Pharmacological intervention and lifestyle modification alter expression of CTRPs in circulation and in metabolically active tissues. CTRPs enhance metabolism and possess insulin sensitizing properties; thus, dysregulated expression of CTRPs in metabolic disorders could contribute to the pathogenesis of the disease. For these reasons, CTRPs appear to be promising targets for early detection, prevention and treatment of metabolic disorders.


In this review article, Ramanjaneya and colleagues explore the role of CTRPs in the metbaolic system.

Articles Recent Most accessed Association between angiotensinogen (AGT), angiotensin-converting enzyme (ACE) and angiotensin-II receptor 1 (AGTR1) polymorphisms and COVID-19 infection in the southeast of Iran: a preliminary case-control study

Authors: Hamid Reza Kouhpayeh, Farhad Tabasi, Mohammad Dehvari, Mohammad Naderi, Gholamreza Bahari, Tahereh Khalili, Courtney Clark, Saeid Ghavami and Mohsen Taheri

Content type: Research

Safety and efficacy of autologous non-hematopoietic enriched stem cell nebulization in COVID-19 patients: a randomized clinical trial, Abu Dhabi 2020

Authors: Yendry Ventura-Carmenate, Fatima Mohammed Alkaabi, Yandy Marx Castillo-Aleman, Carlos Agustin Villegas-Valverde, Yasmine Maher Ahmed, Pierdanilo Sanna, Ayesha Abdulla Almarzooqi, Abeer Abdelrazik, Gina Marcela Torres-Zambrano, Maura Wade-Mateo, David Quesada-Saliba, Loubna Abdel Hadi, Antonio Alfonso Bencomo-Hernandez and Rene Antonio Rivero-Jimenez

Content type: Research

A novel method for maintaining the stability of freshly cultured Mesenchymal stem cells in clinical grade injection ready state without cryopreservation

Authors: Mandana Mohyeddin Bonab, Fatemeh Talebian, Aida Borzabadi, Vahideh Nasr, Azam Abedi Kooshlshahi, Fahime Anisie, Ronaz Haghshenas, Bita Shalbafan, Ehsan Janzamin and Saeed Shahbeigi

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Phi桅Breast theory of spiral cancer new diagnostic techniques for breast cancer detection

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The protective role of statins in COVID-19 patients: a retrospective observational study

Authors: Srikanth Umakanthan, Sanjum Senthil, Stanley John, Mahesh K. Madhavan, Jessica Das, Sonal Patil, Ragunath Rameshwaram, Ananya Cintham, Venkatesh Subramaniam, Madhusudan Yogi, Abhishek Bansal, Sumesh Achutham, Chandini Shekar, Vijay Murthy and Robbin Selvaraj

Content type: Research

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Lost in translation: the valley of death across preclinical and clinical divide 鈥?identification of problems and overcoming obstacles

Authors: Attila A. Seyhan

Content type: Review

Synergy of melanin and vitamin-D may play a fundamental role in preventing SARS-CoV-2 infections and halt COVID-19 by inactivating furin protease

Authors: Kishalay Paria, Debarati Paul, Trinath Chowdhury, Smritikana Pyne, Ranadhir Chakraborty and Santi M. Mandal

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Total lymphocyte count in cancer patients with lymphopenia treated with intravenous vitamin C: Results of an observational study

Authors: Dolores Margarita Rodr铆guez, Mery Elizabeth Guerrero, B谩rbara Marisol Maldonado, Claudia Vollbracht and Sandra Aracely Herrera

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C-C chemokine receptor type 5 links COVID-19, rheumatoid arthritis, and Hydroxychloroquine: in silico analysis

Authors: Mahmood Y. Hachim, Ibrahim Y. Hachim, Kashif Bin Naeem, Haifa Hannawi, Issa Al Salmi and Suad Hannawi

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Statins in patients with COVID-19: a retrospective cohort study in Iranian COVID-19 patients

Authors: Payam Peymani, Tania Dehesh, Farnaz Aligolighasemabadi, Mohammadamin Sadeghdoust, Katarzyna Kotfis, Mazaher Ahmadi, Parvaneh Mehrbod, Pooya Iranpour, Sanaz Dastghaib, Ahmad Nasimian, Amir Ravandi, Biniam Kidane, Naseer Ahmed, Pawan Sharma, Shahla Shojaei, Kamran Bagheri Lankarani

Content type: Research

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Why publish with us Home for all valid research within pre-clinical and translational medicineGold open access and compatible with growing funder mandatesExpert Section Editors and an international Editorial BoardFree access to all content, ensuring a wide dissemination of articlesHigh article accesses with more than 55,900 article downloads in 2020Companion journal to Journal of Translational Medicine Aims and scope

Translational Medicine Communications is an interdisciplinary forum for all scientifically valid research from across translational medicine. We publish research that focuses on the biology of disease, as well as preclinical and basic research that is closely associated with medicine. Translational Medicine Communications will also consider reviews, methodology articles, protocols and commentaries.

Our aim is to improve transparency and reproducibility within translational medicine, which is why we consider research papers regardless of outcome or significance of findings, as well as protocols for future research. We aim to serve the translational science community by publishing all scientifically valid and technically sound articles and we are dedicated to facilitating the communication between basic and clinical science.

Translational Medicine Communications is the companion journal to Journal of Translational Medicine.

Journal of Translational Medicineconsiders articles focusing on information derived from human experimentation to optimise the communication between basic and clinical science.

Explore the companion journal

Editor-in-Chief: Francesco Marincola, Kite Pharma, USA

Dr. Marincola is Global Head of Research at Kite Pharma, Santa Monica, California. He was previously President and Chief Scientific Officer at Refuge Biotechnologies, Menlo Park, California, Distinguished Research Fellow at AbbVie Corporation; Chief Research Officer at Sidra Research, Qatar; and Tenured Investigator at the National Institutes of Health, Maryland. Dr. Marincola founded in 2003 the Journal of Translational Medicine and is the Editor-in-Chief. He is also Editor-in-Chief of Translational Medicine Communications. He is past-president of the Society for the Immunotherapy of Cancer (SITC) and the International Society for Translational Medicine. He edited several books including the SITC-affiliated Cancer Immunotherapy Principles and Practice Textbook. Dr. Marincola is also an award winning fiction author of The Wise Men of Pizzo and Cat Behind the Window.

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