Home | Drug Metabolism Disposition
Time 2020-09-19 20:04:11Web Name: Home | Drug Metabolism Disposition
WebSite: http://dmd.aspetjournals.org
ID:52556
Keywords:
Drug,Home,Disposition,Description:
A two-tiered in vitro approach to de-risk drug candidates for potential bile salt export pump inhibition liabilities in drug discovery Michael J. Hafey, Robert Houle, Keith Q. Tanis, Ian Knemeyer, Jackie Shang, Qing Chen, Andreas Baudy, James Monroe, Frank D. Sistare and Raymond Evers Drug Metabolism and Disposition September 17, 2020, DMD-AR-2020-000086; DOI: https://doi.org/10.1124/dmd.120.000086 A laboratory specific scaling factor to predict the in vivo human clearance of aldehyde oxidase substrates Mailys De Sousa Mendes, Alexandra Orton, Helen Humphries, Barry C. Jones, Iain Gardner, Sibylle Neuhoff and Venkatesh Reddy Drug Metabolism and Disposition September 6, 2020, DMD-AR-2020-000082; DOI: https://doi.org/10.1124/dmd.120.000082 Functional consequences of pravastatin isomerization on OATP1B1 mediated transport Jonathan B. Wagner, Melissa Ruggiero, J. Steven Leeder and Bruno Hagenbuch Drug Metabolism and Disposition September 5, 2020, DMD-AR-2020-000122; DOI: https://doi.org/10.1124/dmd.120.000122 Characterization of Seasonal Pharmacokinetic Variability in Woodchucks Jim Zheng, Scott Balsitis, Rex Santos, Bill J Smith and Raju Subramanian Drug Metabolism and Disposition September 5, 2020, DMD-AR-2020-000140; DOI: https://doi.org/10.1124/dmd.120.000140 Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model Jian Lu, Ang Chen, Xinrun Ma, Xuyang Shang, Yuanjin Zhang, Yuanqing Guo, Mingyao Liu and Xin Wang Drug Metabolism and Disposition September 1, 2020, DMD-AR-2020-000114; DOI: https://doi.org/10.1124/dmd.120.000114 Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats Edwin J. Squirewell, Marci G. Smeltz, Laura Rowland Faux, Lloyd P. Horne, Peter W. Stacpoole and Margaret O. James Drug Metabolism and Disposition September 1, 2020, DMD-AR-2020-000142; DOI: https://doi.org/10.1124/dmd.120.000142 DMD presents important research in pharmacology and toxicology and is a valuable resource in drug design, drug metabolism, drug transport, expression of drug metabolizing enzymes and transporters, and regulation of drug metabolizing enzyme and transporter gene expression. DMD is published continuously. Articles are added as they are ready and assigned to monthly issues. Check this site for new content or sign up for content alerts.EDITOR S CHOICE ARTICLES FOR SEPTEMBER: For an alternate route to this Journal use this URL: http://intl-dmd.aspetjournals.orgTAGS:Drug Home Disposition
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