Upcoming Department Events
Post-doctoral Research Day and BD/Immunology Lecture Award Presentation
Alex Florescu PhD Research Seminar
Special Seminar - Dr. Catherine Larochelle
Department of Immunology 40th Anniversary
Dr. Pailin Chiaranunt - 2024 Schmidt Science Fellow
Congratulations to Dr. Pailin Chiaranunt for being named as one of the 2024 Schmidt Science Fellows!
Dr. Chiaranunt is a PhD alumna from the Department of Immunology within the Temerty Faculty of Medicine, University of Toronto where she researched macrophages and the human microbiome under the supervision of Dr. Arthur Mortha.
More Information:
Schmidt Science Fellows - Dr. Chiaranunt Announcement
University of Toronto Article
The Globe & Mail Article
Faculty Highlight - Dr. Tak Mak's interview on Canada Files
Dr. Tak Mak's interview was featured on PBS on May 7, 2024.
RECENT PUBLICATIONS FROM OUR DEPARTMENT
Chung DC, Ghaedi M, et al. 2024. Characterization of innate lymphoid cell subsets infiltrating melanoma and epithelial ovarian tumors. Oncoimmunology. 13
Hamidzada H, Pascual-Gil S, et al. 2024. Primitive macrophages induce sarcomeric maturation and functional enhancement of developing human cardiac microtissues via efferocytic pathways. Nature Cardiovascular Research.
Chow S, Lee SPN, et al. 2024. Diagnosis of systemic mastocytosis with cryptic deletion of TET2 and DNMT3A resulting from unbalanced translocation. British Journal Of Haematology.
Loves R, Grunebaum E. 2024. FAS signalling pathway is crucial for CAR T cell persistence. Nature Reviews Immunology.
Persaud AT, Khela J, et al. 2024. Virion-incorporated CD14 enables HIV-1 to bind LPS and initiate TLR4 signaling in immune cells. Journal Of Virology.
Ting KKY. 2024. Fructose-induced metabolic reprogramming of cancer cells. Frontiers In Immunology. 15
Mahtani T, Sheth H, et al. 2024. The ion channel TRPV5 regulates B-cell signaling and activation. Frontiers In Immunology. 15
Dhume SH, Balogun K, et al. 2024. Perinatal exposure to atazanavir-based antiretroviral regimens in a mouse model leads to differential long-term motor and cognitive deficits dependent on the NRTI backbone. Frontiers In Molecular Neuroscience. 17
Zannikou M, Fish EN, et al. 2024. Signaling by Type I Interferons in Immune Cells: Disease Consequences. Cancers. 16
Bi PY, Killackey SA, et al. 2024. Cytosolic retention of HtrA2 during mitochondrial protein import stress triggers the DELE1-HRI pathway. Communications Biology. 7
Touahri Y, Hanna J, et al. 2024. Pten regulates endocytic trafficking of cell adhesion and Wnt signaling molecules to pattern the retina. Cell Reports. 43
Ting KKY. 2024. Fructose overconsumption-induced reprogramming of microglia metabolism and function. Frontiers In Immunology. 15
Zakrzewski JL, Suh D, et al. 2024. Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors (Vol 26, pg 453, 2008). Nature Biotechnology. 42:674-674
Paul MS, Saibil SD, et al. 2024. Ex vivo activation of the GCN2 pathway metabolically reprograms T cells, leading to enhanced adoptive cell therapy. Cell Reports Medicine. 5
Lee S, Yeung KKM, et al. 2024. Tissue-resident memory T cells in protective immunity to influenza virus. Current Opinion In Virology. 65
Clotet-Freixas S, Zaslaver O, et al. 2024. Sex differences in kidney metabolism may reflect sex-dependent outcomes in human diabetic kidney disease. Science Translational Medicine. 16
Wang AA, Luessi F, et al. 2024. B cell depletion with anti-CD20 promotes neuroprotection in a BAFF-dependent manner in mice and humans. Science Translational Medicine. 16
Almomani O, Nnamutete J, et al. 2024. Effect of cryopreservation on CD4+T cell subsets in foreskin tissue. PLOS One. 19
Gorczynski R. 2024. Translation of Data from Animal Models of Cancer to Immunotherapy of Breast Cancer and Chronic Lymphocytic Leukemia. Genes. 15
Gommerman JL. 2024. What Jane Jacobs has taught me about neuroimmunology. Nature Immunology. 25:381-381
Ucciferri CC, Gower A, et al. 2024. Scoring Central Nervous System Inflammation, Demyelination, and Axon Injury in Experimental Autoimmune Encephalomyelitis. JOVE-journal Of Visualized Experiments.
Robbrecht D, Grob JJ, et al. 2024. Biomarker and pharmacodynamic activity of the transforming growth factor-beta (TGF?) inhibitor SAR439459 as monotherapy and in combination with cemiplimab in a phase I clinical study in patients with advanced solid tumors. CTS-clinical And Translational Science. 17
Popovic A, Cao EY, et al. 2024. Commensal protist Tritrichomonas musculus exhibits a dynamic life cycle that induces extensive remodeling of the gut microbiota. ISME Journal. 18
Altieri A, Marshall CL, et al. 2024. Human Host Defense Peptide LL-37 Suppresses TNF?-Mediated Matrix Metalloproteinases MMP9 and MMP13 in Human Bronchial Epithelial Cells. Journal Of Innate Immunity. 16:203-215
Last Updated May 29, 2024
COVID-19 INFORMATION
See the basic research related to, and informational pamphlets about the COVID-19 pandemic from our faculty and students.
COVID-19, VACCINES AND HOW THEY WORK
View a presentation from Professor Tania Wattsexplaining the immunology of COVID-19 as well as information relating to the newly developed vaccines.
IMMPress Magazine
In this issue of IMMpress, the interconnectedness of international research is visually represented in a chord diagram resembling earth. A chord diagram is commonly used to illustrate the inter-relationships between entities, with each arc bridging from one point to another to demonstrate their connection. As depicted, research does not occur in isolation; it is intricately connected to not only other research nodes, but the broader world. In a way, we are all integral parts of a larger network of effort aimed at creating a better world for everyone.
UofTMed
UofTMed is an alumni magazine like no other. Bold, ambitious and lively, we dive into medicine’s most pressing topics. Read the latest issue of UofTMed magazine, with all your favourite regular departments and provocative feature articles.