Faculty / Principal Investigators UCLA-DOE Institute

Time 2021-08-19 20:07:30

Web Name: Faculty / Principal Investigators UCLA-DOE Institute

WebSite: http://people.mbi.ucla.edu

ID:187723

Keywords:

Investigators,Principal,Faculty,

Description:

Todd O. Yeates, ProfessorUCLA-DOE Institute DirectorStructural, computational, and synthetic biology. Current focus is on large protein assemblies, including natural structures such as the carboxysome and other bacterial microcompartments, and designed structures built from novel self-assembling protein molecules.Office: (310) 206-4866Lab: (310) 205-8901255 Boyer Hallyeates@mbi.ucla.eduHome Web Page Keriann Backus, Assistant ProfessorALGAL FUNCTIONAL GENOMICSWe investigate how protein function and cellular fate can be studied and manipulated by chemical probes. By developing new methods that combine chemical biology, genomics, and proteomics, we aim to identify functional, disease-linked, and probe-accessible pockets in human proteins. Current applications of our methods include: (i) the production of probes to alter protein interactions, (ii) precision anti-cancer probes, and (iii) probes that enhance T cell proliferation.Departments of Biological Chemistry and Chemistry and BiochemistryHome Web Page James Bowie, ProfessorSYNTHETIC BIOCHEMISTRY: ENZYME AND PATHWAY DESIGNMembrane protein structure, SAM Domains: A Biological Polymer, Synthetic Biochemistry for Green Production of Chemicals and Biofuels.Office: (310) 206-4747Lab: (310) 206-4748Fax: (310) 206-4749655 Boyer Hallbowie@mbi.ucla.eduHome Web Page  Siobhan Braybrook, Assistant ProfessorOur research is aimed at understanding how shapes are physically established and grown in walled organisms. siobhanb (at) ucla.eduHome Web Page Robert T. Clubb, ProfessorMICROBIAL METABOLISM CHEMISTRY AND COMMUNITIESSYNTHETIC BIOCHEMISTRY: ENZYME AND PATHWAY DESIGNEngineering microbial surfaces; Mechanisms of bacterial pathogenesis; Function of cell surface virulence factors in Staphylococcus aureus and Bacillus anthracis; Heteronuclear multidimensional NMR spectroscopy.Office: (310) 206-2334Lab: (310) 226-3044602 Boyer Hallrclubb@mbi.ucla.eduHome Web Page David S. Eisenberg, ProfessorATOMIC IMAGING TECHNOLOGIES AND NOVEL STATES OF MATTER FOR PROTEINSCenter For Global MentoringStudy of biochemical macromolecules by X-ray diffraction and computational methods; structure and action of enzymes and of membrane-related proteins; protein folding and the atomic basis of biological recognition.National Academy of Sciences MemberOffice: (310) 825-3754Lab: (310) 825-8901Fax: (310) 206-3914201 Boyer Halldavid@mbi.ucla.eduHome Web Page Juli Feigon, ProfessorStructure and Function of Non-coding RNAs and RibonucleoproteinsRNA has increasingly been found to have a role in everything from regulation of transcription and translation to synthesis of the ends of chromosomes to enzymatic reactions. In order to do these things, RNA assumes a variety of shapes and often forms specific RNA-protein complexes.feigon (at) mbi.ucla.eduHome Web Page Robert P. Gunsalus, ProfessorMICROBIAL METABOLISM CHEMISTRY AND COMMUNITIESOur research focuses on understanding the physiology and molecular biology of gene regulation in model bacteria and archaea. Emphasis is on the central pathways for cell respiration and carbon flow in pure as well as in co-culturesOffice: (310) 206-8201Fax: (310) 206-5231609 Charles E Young Drrobg@microbio.ucla.eduHome Web Page  Joseph A. Loo, ProfessorDevelopment of novel bioanalytical and proteomics methods for the characterization of proteins and their post-translational modifications. Proteomics of cell surfaces. Development of mass spectrometry for the study of macromolecular complexes, protein-ligand interactions, and their application to structural biology.Office: (310) 794-7023402 Boyer Halljloo@chem.ucla.eduHome Web Page Matteo Pellegrini, ProfessorALGAL FUNCTIONAL GENOMICSMICROBIAL METABOLISM CHEMISTRY AND COMMUNITIESOur lab is interested in the development of computational approaches to interpret genomic data. These methodologies allow us to develop annotated genomes, epigenomes and transcriptomes. Our approach is to integrate these data layers that are produced using the latest generation of high throughput sequencers. For instance we are developing suites of tools for the analysis of DNA methylation data, as well as tools to annotate genomes using RNA sequences.Office: (310) 825-0012Lab: (310) 825-0274Fax: (310) 206-39873000C Terasaki Life Sciences Buildingmatteop@mcdb.ucla.eduHome Web Page  Jose Rodriguez, Assistant ProfessorOur research is aimed at understanding how shapes are physically established and grown in walled organisms. jrodriguez (at) mbi.ucla.eduHome Web PageUCLA-DOE Institute for Genomics Proteomics Awards HonorsClick here

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