MIC EUCAST

Web Name: MIC EUCAST

WebSite: http://mic.eucast.org

ID:199134

Keywords:

MIC,EUCAST,

Description:

Antimicrobial wild type distributions of microorganisms Mic distributions include collated data from multiple sources, geographical areas and time periods and can never be used to infer rates of resistance MIC and Inhibition zone diameter distributions of microorganisms without and with phenotypically evident resistance mechanisms MIC and inhibition zone diameter distributions Distributions are shown as "aggregated distributions" and as "aggregated weighted distributions". For aggregated distributions all accepted distributions (as defined in SOP 10) were added to form one common distribution. For aggregated weighted distributions each individual distribution was converted to contribute equally to the common aggregated distribution. In this way large distributions are prevented from drowning out smaller distributions. 1. MIC distributions The website gives MIC distributions for individual micro-organisms (bacteria and fungi) and antimicrobial agents in tables and histograms. The distributions are based on collated data from an increasing total of more than 30 000 MIC distributions from worldwide sources. Unless otherwise specifically stated, the data are representative of results obtained with MIC methods performed by or calibrated to reference broth microdilution using ISO-20776-2. Different methods do not give exactly the same results, but the results rarely vary by more than one doubling dilution step. In this way the aggregated MIC distributions encompass the variation between different investigators, laboratories, geographic locations and time periods. 2. Inhibition zone diameter distributions The website gives inhibition zone diameter distributions for individual organisms and antimicrobial agents in tables and histograms. The distributions are based on collated data from an increasing number of sources worldwide. The data are representative of results obtained with the EUCAST disk diffusion method (launched in 2009 - see www.eucast.org). Clinical MIC and Zone diameter breakpoints These are not shown on this website – please consult the EUCAST breakpoint tables for bacteria and fungi on www.eucast.org. Epidemiological cut-off values (ECOFF) and tentative epidemiological cut-off values (TECOFF) ECOFFs (and TECOFFs) distinguish microorganisms without (wild type) and with phenotypically detectable acquired resistance mechanisms (non-wild type) to the agent in question. The epidemiological cut-off value is shown in the tables and the bottom left-hand corner of each MIC and zone diameter graph. TECOFFs (ECOFFs in parentheses) are based on 3 or 4 distributions and ECOFFs on at least 5 and up to 100 or more distributions. Limitations The database is being curated in accordance with EUCAST SOP 10. Different studies often use different MIC concentration ranges. Distributions truncated at the lower end of the scale within the putative wild-type distribution have been excluded. The accepted distributions include studies from a wide variety of sources and time periods and some, on purpose, include high and others low, proportions of resistant organisms, so the distributions must not be used to represent rates of resistance to any agent and cannot be used to compare resistance rates among agents, resistance over time or resistance in different geographic locations. To cite data from the EUCAST program We suggest the format "European Committee on Antimicrobial Susceptibility Testing. Data from the EUCAST MIC distribution website, last accessed Day Month Year”. http://www.eucast.org" To contribute MIC- or zone diameter distribution data Please send data to gunnar.kahlmeter@eucast.org or Jenny.ahman@eucast.org. We propose you download from the EUCAST website (https://www.eucast.org/mic_distributions_and_ecoffs/) and use one of the Excel files for bacteria or fungi and follow the instructions in the spreadsheet. Frequently asked questions What is the purpose of the MIC distributions? reference material for committees involved in decisions on clinical breakpoints reference material for epidemiological cut-off values for antimicrobial resistance surveillance reference MIC ranges of wild type organisms for a wide spectrum of species and antimicrobials international reference for calibration of antimicrobial susceptibility testing methods. If your distribution indicate a different wild type and ECOFF value than that in the database, as evidenced by a putative wild-type modal 2 or more two-fold dilutions different from the mode of the website’s aggregated distributions, you probably made a mistake, used inadequate material or have used a method that is neither the reference method or one calibrated to it ECOFFs can be used for antimicrobial resistance surveillance purposes, especially when other breakpoints are poorly defined or change over time The distributions include data from national and international studies and resistance surveillance programs, as well as MIC distributions from published articles, the pharmaceutical industry, veterinary programs and individual laboratories. Which MIC determination and disk diffusion methods are represented? The MIC distributions represent MIC values primarily determined with methods described by EUCAST and CLSI using ISO 20776-1 (ISO 16256 for fungi). Other MIC-determination methods clearly calibrated to any of the reference methods using ISO-20776-2 are also included. Where no internationally agreed reference method exists, the distributions are labelled according to the method used. The zone diameter distributions are based on inhibition zones generated through the EUCAST disk diffusion method only. Have data obtained with a specific method been excluded? For MIC data, no specific method has been excluded. Contributions are screened by the EUCAST Subcommittee on Wild Type distributions and ECOFFs and typically 10 - 20% have been excluded from the aggregated distributions, the most common reason being "lower end truncation". However, all data are held in the database and are accessible for discussion. For inhibition zone diameter data, only data generated with quality-controlled EUCAST disk diffusion methodology have been included. Thus, the upper part, representing organisms without acquired resistance, can be used to calibrate methodology. The wild-type distribution generated in individual laboratories should match the wild type distributions on the EUCAST website (mode within one two-fold dilution). What is the origin of the organisms included in the data? The data are from bacteria and fungi collected from man and animals, of any geographic origin and over a period of 70 years. What does "No Data available" imply? For some of the antimicrobials in the pull-down list no data is available for public view ("No Data available"). The process of harmonizing clinical breakpoints across Europe and of defining the epidemiological cut-off values is co-ordinated with the collection of relevant MIC data. As decisions on breakpoints are made and the quality of data have been assessed for each group of antimicrobials the data are released for public use. Where can I get more information? Contact EUCAST via the EUCAST Contact form. In addition, email addresses and further information can be obtained through the EUCAST website at https://www.eucast.org. The mic.eucast.org website is the EUCAST software for displaying distributions of MIC-values (generated with broth microdilution according to the ISO-standard or with methods calibrated to broth microdilution or when appropriate agar dilution) and inhibition zone diameters (generated only with EUCAST disk diffusion methodology with disks and media from several manufacturers). EUCAST is a standing committee organized by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID). EUCAST is on contract with ECDC (The European Centre for Disease prevention and Control) and provides breakpoints for antibacterial (including Mycobacteria spp.) and antifungal agents (Yeasts, Moulds, Dermatophytes). The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) is a registered non-profit organization in Basel, Switzerland. ESCMID’s VAT number is CHE-499.354.584. Questions regarding the website can be addressed to the ESCMID Executive Office. Editorial Office ESCMID Executive Office, P.O. Box 214, 4010 Basel, Switzerland info[at]escmid.org Web Conception, Realisation Code Red. GmbH, Düsseldorf, Germany mail[at]codered.net Copyright ESCMID maintains the copyright for all material on the mic.eucast website with all rights reserved. Any copyright violation may result in ESCMID protecting its rights. Terms and Conditions of Website Use These terms and conditions govern access to and use of this website, owned and operated by ESCMID. Your use is conditional upon your acceptance and compliance with these terms and conditions. Disclaimer This website is financed entirely by ESCMID – The European Society of Clinical Microbiology and Infectious Diseases and receives no external funding or sponsorship. ESCMID cannot provide any guarantees and cannot be held liable for any errors, inaccuracies or incompleteness of any information given on this website by officers or employees of ESCMID or any other third party the views and opinions expressed by individual authors of articles, presentations or discussion/opinion papers etc. do not necessarily reflect those of ESCMID. Users should be aware that personal or other information they provide for publication on the mic.eucast.org website, will be found by external search engines. ESCMID is not liable in any way and without any limit towards any party for any kind of damage, loss or harm that might be caused by visiting this website. It is not ESCMID’s responsibility to make sure that your system is free of viruses and any other kind of possibly harmful issues. ESCMID does not guarantee that any other site you obtain access. Jurisdiction The European Society of Clinical Microbiology and Infectious Diseases is a non-profit organization registered in Basel, Switzerland. The terms and conditions of this website are governed by and shall be construed in accordance with Swiss law. The parties submit any disputes arising out of, or in connections with, online sales or any aspect of these terms and conditions to the exclusive jurisdiction of the courts of Basel, where they will be judged on their merits, independently of the rules concerning any conflicting legislation. This notice provides ESCMID's policy regarding the nature, purpose, use and sharing of any information collected via this website (mic.eucast.org). The information you provide will be used only for its intended purpose. Submitting information is strictly voluntary. By doing so, you are giving ESCMID your permission to use the information for the intended purpose. ESCMID never collects information for commercial marketing. ESCMID does not give your information to any private or other organisation for their use. The use of the Internet pages of mic.eucast.org is possible without any indication of personal data; however, if a data subject wants to use special enterprise services via our website, processing of personal data could become necessary. If the processing of personal data is necessary and there is no statutory basis for such processing, we generally obtain consent from the data subject. The processing of personal data, such as the name, address, e-mail address, or telephone number of a data subject shall always be in line with the General Data Protection Regulation (GDPR), and in accordance with the country-specific data protection regulations applicable to ESCMID. By means of this data protection declaration, our enterprise would like to inform the general public of the nature, scope, and purpose of the personal data we collect, use and process. Furthermore, data subjects are informed, by means of this data protection declaration, of the rights to which they are entitled. As the controller, ESCMID has implemented numerous technical and organizational measures to ensure the most complete protection of personal data processed through this website. However, Internet-based data transmissions may in principle have security gaps, so absolute protection may not be guaranteed. For this reason, every data subject is free to transfer personal data to us via alternative means, e.g. by telephone. 1. Definitions The data protection declaration of ESCMID is based on the terms used by the European legislator for the adoption of the General Data Protection Regulation (GDPR). Our data protection declaration should be legible and understandable for the general public, as well as our customers and business partners. To ensure this, we would like to first explain the terminology used. In this data protection declaration, we use, inter alia, the following terms: a) Personal data Personal data means any information relating to an identified or identifiable natural person (“data subject”). An identifiable natural person is one who can be identified, directly or indirectly, in particular by reference to an identifier such as a name, an identification number, location data, an online identifier or to one or more factors specific to the physical, physiological, genetic, mental, economic, cultural or social identity of that natural person. b) Data subject Data subject is any identified or identifiable natural person, whose personal data is processed by the controller responsible for the processing. c) Processing Processing is any operation or set of operations which is performed on personal data or on sets of personal data, whether or not by automated means, such as collection, recording, organisation, structuring, storage, adaptation or alteration, retrieval, consultation, use, disclosure by transmission, dissemination or otherwise making available, alignment or combination, restriction, erasure or destruction. d) Restriction of processing Restriction of processing is the marking of stored personal data with the aim of limiting their processing in the future. e) Profiling Profiling means any form of automated processing of personal data consisting of the use of personal data to evaluate certain personal aspects relating to a natural person, in particular to analyse or predict aspects concerning that natural person's performance at work, economic situation, health, personal preferences, interests, reliability, behaviour, location or movements. f) Pseudonymisation Pseudonymisation is the processing of personal data in such a manner that the personal data can no longer be attributed to a specific data subject without the use of additional information, provided that such additional information is kept separately and is subject to technical and organisational measures to ensure that the personal data are not attributed to an identified or identifiable natural person. g) Controller or controller responsible for the processing Controller or controller responsible for the processing is the natural or legal person, public authority, agency or other body which, alone or jointly with others, determines the purposes and means of the processing of personal data; where the purposes and means of such processing are determined by Union or Member State law, the controller or the specific criteria for its nomination may be provided for by Union or Member State law. h) Processor Processor is a natural or legal person, public authority, agency or other body which processes personal data on behalf of the controller. i) Recipient Recipient is a natural or legal person, public authority, agency or another body, to which the personal data are disclosed, whether a third party or not. However, public authorities which may receive personal data in the framework of a particular inquiry in accordance with Union or Member State law shall not be regarded as recipients; the processing of those data by those public authorities shall be in compliance with the applicable data protection rules according to the purposes of the processing. j) Third party Third party is a natural or legal person, public authority, agency or body other than the data subject, controller, processor and persons who, under the direct authority of the controller or processor, are authorised to process personal data. k) Consent Consent of the data subject is any freely given, specific, informed and unambiguous indication of the data subject's wishes by which he or she, by a statement or by a clear affirmative action, signifies agreement to the processing of personal data relating to him or her. 2. Name and Address of the controller Controller for the purposes of the General Data Protection Regulation (GDPR), other data protection laws applicable in Member states of the European Union and other provisions related to data protection is: ESCMID Executive Office P.O. Box 214 4010 Basel Switzerland info[at]escmid.org 3. Collection of general data and information The website of mic.eucast.org collects a series of general data and information when a data subject or automated system calls up the website. This general data and information are stored in the server log files. We may collect and temporarily store certain technical information about your visit to use for site management and security purposes. This information includes: The internet domain from which you access our Website (for example, "xcompany.com" if you use a private Internet access account, or "yourschool.edu" if you connect from an educational domain); The IP address (a unique number for each computer connected to the Internet) from which you access our Website; The type of browser (e.g., Netscape, Internet Explorer) used to access our site; The operating system (Windows, Unix) used to access our site; The date and time you access our site; The URLs of the pages you visit; If you visited this website from another Website, the URL of the forwarding site. This information is only used to help us make our site more useful for you. From this data we learn about the number of visitors to our site and the types of technology our visitors use. Except for authorized law enforcement investigations, no attempts are made to identify individual users or their usage habits. Raw data logs are retained temporarily as required for security and site management purposes only. When using these general data and information, ESCMID does not draw any conclusions about the data subject. Rather, this information is needed to (1) deliver the content of our website correctly, (2) optimize the content of our website as well as its advertisement, (3) ensure the long-term viability of our information technology systems and website technology, and (4) provide law enforcement authorities with the information necessary for criminal prosecution in case of a cyber-attack. Therefore, ESCMID analyzes anonymously collected data and information statistically, with the aim of increasing the data protection and data security of our enterprise, and to ensure an optimal level of protection for the personal data we process. The anonymous data of the server log files are stored separately from all personal data provided by a data subject. In addition, this website uses matomo, an open-source web analytics software that uses cookies to collect information about how our website is used. These cookies do not collect personal data. The data collected is only used to improve the website and cannot be traced to you. You can set your cookie preferences when you visit our website for the first time, and later change them by following this link: Manage cookie settings. Cookies are small text files that are placed in browser directories on your computer or mobile device when you visit our Websites. Our Websites use session cookies and persistent cookies. Session cookies enable our Websites to remember any information you have already entered when you move from page to page within one of our Websites. A session cookie is deleted either when you close your browser or after a short time. Persistent cookies allow the Websites to remember your preferences and settings when you visit the Websites in the future. Persistent cookies expire after a set period of time. You can change your browser settings to block cookies or to alert you when cookies are being sent to your device. Please note that if you decide to disable cookies, you may not be able to access certain functions of our Websites or marketing communications. 4. Routine erasure and blocking of personal data The data controller shall process and store the personal data of the data subject only for the period necessary to achieve the purpose of storage, or as far as this is granted by the European legislator or other legislators in laws or regulations to which the controller is subject to. If the storage purpose is not applicable, or if a storage period prescribed by the European legislator or another competent legislator expires, the personal data are routinely blocked or erased in accordance with legal requirements. 5. Rights of the data subject a) Right of confirmation Each data subject shall have the right granted by the European legislator to obtain from the controller the confirmation as to whether or not personal data concerning him or her are being processed. If a data subject wishes to avail himself of this right of confirmation, he or she may, at any time, contact any employee of the controller. b) Right of access Each data subject shall have the right granted by the European legislator to obtain from the controller free information about his or her personal data stored at any time and a copy of this information. Furthermore, the European directives and regulations grant the data subject access to the following information: the purposes of the processing; the categories of personal data concerned; the recipients or categories of recipients to whom the personal data have been or will be disclosed, in particular recipients in third countries or international organisations; where possible, the envisaged period for which the personal data will be stored, or, if not possible, the criteria used to determine that period; the existence of the right to request from the controller rectification or erasure of personal data, or restriction of processing of personal data concerning the data subject, or to object to such processing; the existence of the right to lodge a complaint with a supervisory authority; where the personal data are not collected from the data subject, any available information as to their source; the existence of automated decision-making, including profiling, referred to in Article 22(1) and (4) of the GDPR and, at least in those cases, meaningful information about the logic involved, as well as the significance and envisaged consequences of such processing for the data subject. Furthermore, the data subject shall have a right to obtain information as to whether personal data are transferred to a third country or to an international organisation. Where this is the case, the data subject shall have the right to be informed of the appropriate safeguards relating to the transfer. If a data subject wishes to avail himself of this right of access, he or she may, at any time, contact any employee of the controller. c) Right to rectification Each data subject shall have the right granted by the European legislator to obtain from the controller without undue delay the rectification of inaccurate personal data concerning him or her. Taking into account the purposes of the processing, the data subject shall have the right to have incomplete personal data completed, including by means of providing a supplementary statement. If a data subject wishes to exercise this right to rectification, he or she may, at any time, contact any employee of the controller. d) Right to erasure (Right to be forgotten) Each data subject shall have the right granted by the European legislator to obtain from the controller the erasure of personal data concerning him or her without undue delay, and the controller shall have the obligation to erase personal data without undue delay where one of the following grounds applies, as long as the processing is not necessary: The personal data are no longer necessary in relation to the purposes for which they were collected or otherwise processed. The data subject withdraws consent to which the processing is based according to point (a) of Article 6(1) of the GDPR, or point (a) of Article 9(2) of the GDPR, and where there is no other legal ground for the processing. The data subject objects to the processing pursuant to Article 21(1) of the GDPR and there are no overriding legitimate grounds for the processing, or the data subject objects to the processing pursuant to Article 21(2) of the GDPR. The personal data have been unlawfully processed. The personal data must be erased for compliance with a legal obligation in Union or Member State law to which the controller is subject. The personal data have been collected in relation to the offer of information society services referred to in Article 8(1) of the GDPR. If one of the aforementioned reasons applies, and a data subject wishes to request the erasure of personal data stored by ESCMID, he or she may, at any time, contact any employee of the controller. An employee of ESCMID shall promptly ensure that the erasure request is complied with immediately. Where the controller has made personal data public and is obliged pursuant to Article 17(1) to erase the personal data, the controller, taking account of available technology and the cost of implementation, shall take reasonable steps, including technical measures, to inform other controllers processing the personal data that the data subject has requested erasure by such controllers of any links to, or copy or replication of, those personal data, as far as processing is not required. An employees of the ESCMID will arrange the necessary measures in individual cases. e) Right of restriction of processing Each data subject shall have the right granted by the European legislator to obtain from the controller restriction of processing where one of the following applies: The accuracy of the personal data is contested by the data subject, for a period enabling the controller to verify the accuracy of the personal data. The processing is unlawful and the data subject opposes the erasure of the personal data and requests instead the restriction of their use instead. The controller no longer needs the personal data for the purposes of the processing, but they are required by the data subject for the establishment, exercise or defence of legal claims. The data subject has objected to processing pursuant to Article 21(1) of the GDPR pending the verification whether the legitimate grounds of the controller override those of the data subject. If one of the aforementioned conditions is met, and a data subject wishes to request the restriction of the processing of personal data stored by ESCMID, he or she may at any time contact any employee of the controller. The employee of ESCMID will arrange the restriction of the processing. f) Right to data portability Each data subject shall have the right granted by the European legislator, to receive the personal data concerning him or her, which was provided to a controller, in a structured, commonly used and machine-readable format. He or she shall have the right to transmit those data to another controller without hindrance from the controller to which the personal data have been provided, as long as the processing is based on consent pursuant to point (a) of Article 6(1) of the GDPR or point (a) of ,Article 9(2) of the GDPR, or on a contract pursuant to point (b) of Article 6(1) of the GDPR, and the processing is carried out by automated means, as long as the processing is not necessary for the performance of a task carried out in the public interest or in the exercise of official authority vested in the controller. Furthermore, in exercising his or her right to data portability pursuant to Article 20(1) of the GDPR, the data subject shall have the right to have personal data transmitted directly from one controller to another, where technically feasible and when doing so does not adversely affect the rights and freedoms of others. In order to assert the right to data portability, the data subject may at any time contact any employee of the ESCMID. g) Right to object Each data subject shall have the right granted by the European legislator to object, on grounds relating to his or her particular situation, at any time, to processing of personal data concerning him or her, which is based on point (e) or (f) of Article 6(1) of the GDPR. This also applies to profiling based on these provisions. ESCMID shall no longer process the personal data in the event of the objection, unless we can demonstrate compelling legitimate grounds for the processing which override the interests, rights and freedoms of the data subject, or for the establishment, exercise or defence of legal claims. If ESCMID processes personal data for direct marketing purposes, the data subject shall have the right to object at any time to processing of personal data concerning him or her for such marketing. This applies to profiling to the extent that it is related to such direct marketing. If the data subject objects to ESCMID to the processing for direct marketing purposes, ESCMID will no longer process the personal data for these purposes. In addition, the data subject has the right, on grounds relating to his or her particular situation, to object to processing of personal data concerning him or her by ESCMID for scientific or historical research purposes, or for statistical purposes pursuant to Article 89(1) of the GDPR, unless the processing is necessary for the performance of a task carried out for reasons of public interest. In order to exercise the right to object, the data subject may contact any employee of ESCMID. In addition, the data subject is free in the context of the use of information society services, and notwithstanding Directive 2002/58/EC, to use his or her right to object by automated means using technical specifications. h) Automated individual decision-making, including profiling Each data subject shall have the right granted by the European legislator not to be subject to a decision based solely on automated processing, including profiling, which produces legal effects concerning him or her, or similarly significantly affects him or her, as long as the decision (1) is not is necessary for entering into, or the performance of, a contract between the data subject and a data controller, or (2) is not authorised by Union or Member State law to which the controller is subject and which also lays down suitable measures to safeguard the data subject's rights and freedoms and legitimate interests, or (3) is not based on the data subject's explicit consent. If the decision (1) is necessary for entering into, or the performance of, a contract between the data subject and a data controller, or (2) it is based on the data subject's explicit consent, ESCMID shall implement suitable measures to safeguard the data subject's rights and freedoms and legitimate interests, at least the right to obtain human intervention on the part of the controller, to express his or her point of view and contest the decision. If the data subject wishes to exercise the rights concerning automated individual decision-making, he or she may, at any time, contact any employee of ESCMID. i) Right to withdraw data protection consent Each data subject shall have the right granted by the European legislator to withdraw his or her consent to processing of his or her personal data at any time. If the data subject wishes to exercise the right to withdraw the consent, he or she may, at any time, contact any employee of the ESCMID. 6. Legal basis for the processing Art. 6(1) lit. a GDPR serves as the legal basis for processing operations for which we obtain consent for a specific processing purpose. If the processing of personal data is necessary for the performance of a contract to which the data subject is party, as is the case, for example, when processing operations are necessary for the supply of goods or to provide any other service, the processing is based on Article 6(1) lit. b GDPR. The same applies to such processing operations which are necessary for carrying out pre-contractual measures, for example in the case of inquiries concerning our products or services. Is our company subject to a legal obligation by which processing of personal data is required, such as for the fulfillment of tax obligations, the processing is based on Art. 6(1) lit. c GDPR. In rare cases, the processing of personal data may be necessary to protect the vital interests of the data subject or of another natural person. This would be the case, for example, if a visitor were injured in our company and his name, age, health insurance data or other vital information would have to be passed on to a doctor, hospital or other third party. Then the processing would be based on Art. 6(1) lit. d GDPR. Finally, processing operations could be based on Article 6(1) lit. f GDPR. This legal basis is used for processing operations which are not covered by any of the abovementioned legal grounds, if processing is necessary for the purposes of the legitimate interests pursued by our company or by a third party, except where such interests are overridden by the interests or fundamental rights and freedoms of the data subject which require protection of personal data. Such processing operations are particularly permissible because they have been specifically mentioned by the European legislator. He considered that a legitimate interest could be assumed if the data subject is a client of the controller (Recital 47 Sentence 2 GDPR). 7. The legitimate interests pursued by the controller or by a third party Where the processing of personal data is based on Article 6(1) lit. f GDPR our legitimate interest is to carry out our business in favor of the well-being of all our employees and the shareholders. 8. Period for which the personal data will be stored The criteria used to determine the period of storage of personal data is the respective statutory retention period. After expiration of that period, the corresponding data is routinely deleted, as long as it is no longer necessary for the fulfillment of the contract or the initiation of a contract. 9. Provision of personal data as statutory or contractual requirement; Requirement necessary to enter into a contract; Obligation of the data subject to provide the personal data; possible consequences of failure to provide such data We clarify that the provision of personal data is partly required by law (e.g. tax regulations) or can also result from contractual provisions (e.g. information on the contractual partner). Sometimes it may be necessary to conclude a contract that the data subject provides us with personal data, which must subsequently be processed by us. The data subject is, for example, obliged to provide us with personal data when our company signs a contract with him or her. The non-provision of the personal data would have the consequence that the contract with the data subject could not be concluded. Before personal data is provided by the data subject, the data subject must contact any employee. The employee clarifies to the data subject whether the provision of the personal data is required by law or contract or is necessary for the conclusion of the contract, whether there is an obligation to provide the personal data and the consequences of non-provision of the personal data. 10. Existence of automated decision-making As a responsible company, we do not use automatic decision-making or profiling. 11. Updates to this Privacy Notice We reserve the right to update and change this Privacy Notice from time to time in order to reflect any changes to the way in which we process your personal information or changing legal requirements. Any changes we may make to the Privacy Notice in the future will be posted on this website. Please check back frequently to see any updates or changes to the Privacy Notice. Basel, 17 March 2021

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