Dr John M – cardiac electrophysiologist, cyclist, learner

Web Name: Dr John M – cardiac electrophysiologist, cyclist, learner

WebSite: http://www.drjohnm.org

ID:81029

Keywords:

cardiac,John,Dr,

Description:

The EXCEL trial pitted stents vs bypass surgery for people who have left main coronary artery disease. The trial has been beset with controversy. The three areas of debate surround the definition of MI (or heart attack), the increased risk of death in the stent arm, and selective publishing of data.You should study this one because it hints at how precarious medical evidence can be. On the This Week in Cardiology podcast, I discuss EXCEL, but also the issue of trust in science. This includes a few words on the matter of silly studies that still garner media attention. I ve come to name these studies, howlers. One of the reasons behind this is the business model of medical publishing. Medical journals, like any media outlet, need attention. Coffee studies bring attention; statistics studies not so much. A classic example is the broken study on cardiac MRI in recovered COVID patients. This one had to be corrected due to a slew of errors and now shows no concerning signal of cardiac harm from COVID. But it has hundreds of thousands of page views and will surely bump up the impact factor of the journal that published it. The problem with howlers is that they hurt public trust in science. One week coffee is good, the next it is not. Don t wear masks, do wear masks. Science leaders, I think, ought to be more candid about the limits of science, the uncertainty. Let the public in on the truth. Finally, there was big news in nutrition science: a group at the UCSF actually did a randomized controlled trial. This is huge because most nutrition science stems from flawed observational studies. Let me know what you think. Remember, if you like the pod, give it a good rating so others can find it. It's about 20 minutes. Dr Bob Kaplan from Stanford also spoke on issues relating to how FDA approves drugs--a timely topic. In a provocative piece on the newsletter Persuasion, Dr. Sally Satel argued for caution in the matter of doctors becoming political activists. The good news is that most people infected with coronavirus don't need a hospital or doctor. But some do. Some get very ill.

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cardiac electrophysiologist, cyclist, learner

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