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About UsBoard of AdvisorsContactMALARIA.comA Malaria Information and Community PortalHomeMalaria OverviewMalaria ResearchNewsVideosBlogsMalaria Q AEventsJobsBad drugs: How Falsified and Poor Quality Medicine is Hampering the Fight Against MalariaMalaria.com is delighted to present this latest e-issue in partnership with WWARN (the WorldWide Antimalarial Resistance Network). WWARN focuses on gathering data and collating resources related to malaria medication, and specifically factors affecting its efficacy. READ MORE>>FALSIFIED MEDICINES ISSUEFive Things You Might Not Know About Medicine QualityHow Can We Detect Poor Quality Medicines?Challenges in Tackling the Issue of Poor Quality MedicinesHot Spots: Recent Evidence on the Quality of Currently Recommended AntimalarialsBlog PostsAre We Doing Enough for Malaria Research?By Claire Standley, EditorGiven the current reliance on international donor support as described by the MalaFA report, within the context of malaria research, is funding going to the countries that need it the most?To what extent are operational or implementation research projects receiving funding support, as compared to other types of research (such as basic research)?10 Non-traditional Ways People Get Rid of Mosquito BitesBy Malaria.comMosquito bites itch, and they almost always seem to come at the worst possible time. Given it’s a problem pretty much everyone around the world encounters, lots of people are trying to find creative ways to get rid of them. Below are 10 interesting methods used to combat mosquitoes and their bites. Malaria OverviewMalaria FAQThe History of MalariaMalaria Symptoms and CausesMalaria Countries and MapMalaria PreventionMalaria TreatmentMalaria Prevention and ControlTravel InformationAnopheles MosquitoesNew Research May Lead to Rapid Screening Test for Subclinical InfectionsWhile the global health community has made great strides toward eradicating malaria through prevention and treatment strategies, rapid and inexpensive methods to diagnose submicroscopic malaria in individuals who have no clinical symptoms and undetectable levels of disease-causing parasites in their blood remain an unmet need. New research could pave the way for a rapid screening test capable of diagnosing submicroscopic infectionsWHO: Urgent Call for End to Malaria ResurgenceThe World Health Organization is joining a worldwide call to stop a resurgence of malaria that threatens much of the progress made over the past decade. To mark World Malaria Day, WHO is pushing for urgent action and money to get the global fight against this ancient scourge back on track.Four Year Old Dies of Malaria in ItalyA four-year old girl has died of a severe form of malaria contracted in Italy, where the disease is supposed to have been eradicated years ago nearly half a century ago. Italy s health ministry on Tuesday said it was sending experts to investigate the death Sofia Zago, who died in hospital in the northern city of Brescia overnight between Sunday and Monday.U.S. President s Malaria InitiativeDespite substantial financial contributions by the United States President’s Malaria Initiative (PMI) since 2006, no studies have carefully assessed how this program may have affected important population-level health outcomes. We utilized multiple publicly available data sources to evaluate the association between introduction of PMI and child mortality rates in sub-Saharan Africa (SSA). Methods and findings [ ]Malaria Intervention in Schools Leads to Improvements in Student PerformanceNew research suggests that the ability of children in Africa to perform well in school could be dramatically improved through basic malaria education and treatment. While less fatal among older children, malaria infections often reduce a child s ability to concentrate.More Malaria News...ResearchKSHV Oral Shedding and Plasma Viremia Result in Significant Changes in the Extracellular Tumorigenic miRNA Expression Profile in Individuals Infected with the Malaria ParasiteIn the current study, the host and viral extracellular mature miRNA expression profiles were analyzed in blood of KS-negative individuals in Uganda, comparing those with or without KSHV detectable from the oropharynx.Tools and Strategies for Malaria Control and Elimination: What Do We Need to Achieve a Grand Convergence in Malaria?Progress made in malaria control during the past decade has prompted increasing global dialogue on malaria elimination and eradication. The product development pipeline for malaria has never been stronger, with promising new tools to detect, treat, and prevent malaria, including innovative diagnostics, medicines, vaccines, vector control products, and improved mechanisms for surveillance and response. Does High-Dose Antimicrobial Chemotherapy Prevent the Evolution of Resistance?High-dose chemotherapy has long been advocated as a means of controlling drug resistance in infectious diseases but recent empirical studies have begun to challenge this view. Researchers have developed a general framework for modeling and understanding resistance emergence based on principles from evolutionary biology.Targeting the Cell Stress Response of Plasmodium Falciparum to Overcome Artemisinin ResistanceSuccessful control of falciparum malaria depends greatly on treatment with artemisinin combination therapies. Thus, reports that resistance to artemisinins (ARTs) has emerged, and that the prevalence of this resistance is increasing, are alarming. The researchers model predicts that extending current three-day ART treatment courses to four days, or splitting the doses, will efficiently clear resistant parasite infections. Challenges in Modelling Infectious DIsease DynamicsMalaria, HIV, and tuberculosis (TB) collectively account for several million deaths each year, with all three ranking among the top ten killers in low-income countries. Despite being caused by very different organisms, malaria, HIV, and TB present a suite of challenges for mathematical modellers that are particularly pronounced in these infections, but represent general problems in infectious disease modelling, and highlight many of the challenges described throughout this issue. Here, we describe some of the unifying challenges that arise in modelling malaria, HIV, and TB, including variation in dynamics within the host, diversity in the pathogen, and heterogeneity in human contact networks and behaviour. Through the lens of these three pathogens, we provide specific examples of the other challenges in this issue and discuss their implications for informing public health efforts.Read All ResearchStay Informed WWARN CornerAbout WWARNThe WorldWide Antimalarial Resistance Network (WWARN) generates innovative resources and reliable evidence to inform the malaria community on the factors affecting the efficacy of antimalarial medicines. Learn more Fighting Malaria Requires Protecting the Effectiveness of Antimalarial MedicinesData Sharing at IDDOEvidence to inform equitable dosing in very young and malnourished childrenMore WWARN Stories...HomeMalaria OverviewMalaria ResearchNewsVideosBlogsMalaria Q AEventsJobsAbout UsBoard of AdvisorsContactCopyright 2020 Malaria.com · Log in

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