Home | Swiss National Center of Competence in Research RNA & Disease

Web Name: Home | Swiss National Center of Competence in Research RNA & Disease

WebSite: http://www.nccr-rna-and-disease.ch

ID:338157

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National Center of Competence
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Welcome to the Swiss National Center
of Competence in Research RNA & Disease

The role of RNA in disease mechanisms


News

Biological Distance Determination by a Single Protein Molecule

The Schneider lab in collaboration with the Ochsenreiter group (both University of Bern) researched how the mitocondrial…

Molecular Snapshots of CRISPR Target Recognition & Activation

The mechanism by which CRISPR Cas9 recognizes a target site and subsequently gets activated has not been understood in…

Novel Approach for Detection of Cellular Variation

The Pieters and Zavolan Labs developed a novel approach based on single-cell RNA Sequencing to detect biological…

Boosting HDR by Retargeting CRISPR

To cut genomic DNA and paste from a donor CRISPR-Cas genome editing, requires homolog-directed repair (HDR), but the…

Old & New Transposons are differently excised from DNA in ciliates

Genomes need to keep the transposons they contain silenced. In ciliates, the silencing occurs in the soma by excising…

Scaffolding the mRNA 3' End Biogenesis Complex

To cleave and polyadenylate pre-mRNA, the assembly of a 1.5 megadalton complex is required. The center part of this…Follow @NCCR_RNADiseaseTweets by NCCR_RNADisease

The central molecule of life

RNA functions as a carrier of genetic information, as a biocatalyst, and exerts crucial regulatory functions in the cell. Arrows indicate the flow of genetic information and regulatory functions.


molecool.ch - our public window on researching rna


Events

03 October 202216:30–17:30

Juli Feigon - NCCR Seminar Series (BE)

DCBP U113, University of Bern

04 October 202216:00–17:00

Juli Feigon - NCCR Seminar Series (ZH)

HCI G3, ETH Zurich

10 October 202216:30–17:30

Archa Fox - NCCR Seminar Series (BE)

DCBP U113, University of Bern

All events


Recent Publications

MicroRNA-7 regulates melanocortin circuits involved in mammalian energy homeostasisSingle p197 molecules of the mitochondrial genome segregation system of Trypanosoma brucei determine the distance between basal body and outer membraneImpaired immune response drives age-dependent severity of COVID-19E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidationTake a break: Transcription regulation and RNA processing by the Integrator complex

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Recent Preprints

A rapid protocol for ribosome profiling of low input samplesPharmacological inhibition of bromodomain and extra-terminal proteins induces NRF-2-mediated inhibition of SARS-CoV-2 replication and is subject to viral antagonismTransCistor reveals the landscape of cis-regulatory long noncoding RNAsA hybrid structure determination approach to investigate the druggability of the nucleocapsid protein of SARS-CoV-2An Alpha-helical Lid Guides the Target DNA toward Catalysis in CRISPR-Cas12a

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