Blood and Marrow Transplantation | Blood Marrow Transplantation | Stanford Medicine

Web Name: Blood and Marrow Transplantation | Blood Marrow Transplantation | Stanford Medicine

WebSite: http://bmt.stanford.edu

ID:49748

Keywords:

Marrow,and,Blood,

Description:

Welcome to Blood & Marrow TransplantationWorld Class Expertise in Patient Care and Research Welcome to the Division of Blood and Marrow Transplantation. We are very proud of the outstanding compassionate care that we provide our patients along with conducting state of the art basic and translational science on stem cell biology, cellular immunology and transplantation biology. The BMT program at Stanford performs autologous and allogeneic transplantations for over 450 patients each year. The program has been very successful with a history of limited morbidity rates and acute mortality that is well below most published reports. Our cutting-edge research is developing novel immunotherapy for cancer. Support the BMT Division by making a donation to our research fund.  Two is Better Than One: Arming the T-Cells with Dual Cancer-Targeting Antibodies One way to bring the powerful cellular immunity and antibody directedtargeting together is to construct the chimeric antigen receptor (CAR) T-cells. In this strategy, the patient’s own T-cells are genetically engineered to produce a hybrid molecule (the CAR) on these killing cells. Precision Medicine: New Technology That Changes the Clinical Practice In order to monitor disease after a curative treatment such as allogeneic transplant, pioneer works from Drs. David Miklos and Wen-Kai Weng have established the utility of high-throughput sequencing (HTS) of either B-cell receptor (BCR) or T-cell receptor (TCR) in monitoring minimal residual disease (MRD). Teaching a young dog new tricks: Story of a kinase and its inhibitor The development of normal lymphocytes is a well-orchestrated process, that begins in the bone marrow. This process involves a functional antigen receptor (B-cell receptor or T-cell receptor) and a dozen of intermediators, including adaptor proteins and kinases that form a network of signaling pathways inside the cells. The many challenges to success Since the establishment of Stanford BMT program in 1987, many aspects of the clinical practice have changed. Over 400 patients received bone marrow or stem cell transplants at Stanford last year.

TAGS:Marrow and Blood 

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