HERACLES

Time 2022-09-02 10:26:56

Web Name: HERACLES

WebSite: http://www.heracles-fp7.eu

ID:300723

Keywords:

HERACLES

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Heracles project

New approach needed to tackle parasitic liver disease in Europe and Turkey

31 August 2018 | Geneva –– A cross-sectional study conducted in Bulgaria, Romania and Turkey has found that the true burden of cystic echinococcosis is poorly understood and that many cases remain asymptomatic, with no appropriate medical diagnosis and treatment. The study assessed the prevalence of the disease among rural populations in the three countries. more

HERACLES' extended network

Our interactive map allows easy geolocation of the whole HERACLES' network with all the involved institutes (Consortium, Extended Network, Advisory Board) more

New article from the World Health Organization

The burden of CE in Eastern Europe (ultrasound surveys)

Prevalence of abdominal cystic echinococcosis in rural Bulgaria, Romania and Turkey more

The Lancet Infectious Diseases
Volume 18 - Issue 7 - July 2018

© Elsevier Limited / Kouzou Sakai
/ FolioArt

Cystic Echinococcosis (CE) is a chronic helminthic disease caused by the infection with the larval stage (metacestode) of the tapeworm Echinococcus granulosus complex. Human CE is estimated in 2-3 million global cases. Disability-adjusted life years (DALYs) and monetary losses resulting from humanCEhavebeencalculatedatthegloballevel(assumingsubstantialunder-reporting) as high as 1 million (M) DALYs, or an annual loss of US$ 3 billion (annual cost for treating human cases and livestock industry compensation).

Data reported from EU countries represent the tip of the iceberg. The invisible portion includes health, social and economic consequences linked to the people affected by CE. In fact, clinically diagnosed cases represent only a small proportion of the total number of infected people (only those that receive medical attention at the hospital level) and they do not reflect the true incidence or prevalence of CE.

There is an urgent need to raise the awareness of CE and bring the magnitude of the problem to the attention of policymakers and general public in these countries. For these reasons HERACLES collaborative project is designed to provide new insights into parasite/host relationship associated with the epidemiology, clinical manifestation, parasite infectivity, host immunity, improvement of therapeutic treatment and new tools for the detection, diagnosis and follow-up of CE. HERACLES will translate the research results into affordable and easy-to-use, point-of-care commercial tools (POC-LOC) for its use in less favored Eastern European countries (EEC) affected by CE. We will deliver a methodology and an amount of data, exploitable in new diagnostic tools for epidemiological surveillance in animals, and diagnosis and follow up in humans. Moreover, the European Registry of Cystic Echinococcosis (ERCE) will be created to provide baseline data for future risk calculations and to establish a prospective case retrieval. The final project stakeholders, such as the rural populations, in which CE is endemic, as well as SMEs will be engaged as an integral part of the work. Special events to increase general awareness and training activities for improving the health care will be organized.

HERACLES will address all these aspects at the same time thanks to the interdisciplinary expertise of its members thus making a direct impact on the National Health Systems of the EEC involved in the project. Any lessons learned are likely to be applicable and useful for other countries where CE represents an important health problem. To summarize, CE remains a chronic disease, complex and still neglected.

The research leading to these results has received funding
from the European Union Seventh Framework Programme
(FP7/2007-2013) under grant agreement n° 602051

ERCE

European
Register of
Cystic
Echinococcosis

News and events

Final meeting in Rome
(17th - 18th September 2018) agenda participant list Info
Scientific papers currently accepted in peer-reviewed journals: 45 (May 2018)

Cross-sectional ultrasound study: First "original research" ever published by The Lancet Infectious Diseases on echinococcosis (May 2018)

The Heracles' extended networks with more than 60 centres in 30 countries.
(May 2018)

1.799 patients enrolled in the European Register (ERCE). (March 2018)


News archive

Project details

Project number: 602051

Project title:
HERACLES - Human cystic
Echinococcosis ReseArch
in CentraL and Eastern
Societies

Call (part) identifier:
FP7-HEALTH-2013-INNOVATION-1

Start date: 01/10/2013
Duration: 60 months

Coordinator:

ISTITUTO SUPERIORE DI SANITÀ (Italy)

Dr. Adriano Casulli

EC Contribution:
Euro 2.861.500,00
Total cost of the project:
Euro 3.784.916,00

Comunication

Links

Importantes avances
en el gran proyecto europeo contra la hidatidosis

Documents download

HERACLES
leaflet 2018 HERACLES
achievements

last update: 31/10/2018

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