You may be able to save on your next Suboxone Sublingual Film prescription*†

INDICATION

SUBOXONE(buprenorphine and naloxone) Sublingual Film^{® (CIII) is a prescription medicine used to treat opioid addiction in adults and is part of a complete treatment program that also includes counseling and behavioral therapy.}

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about SUBOXONE Sublingual Film?

Keep SUBOXONE Sublingual Film in a secure place out of sight and reach of children, and in a location not accessible by others, including visitors to the home. Accidental use by a child is a medical emergency and can result in death. If a child accidentally takes SUBOXONE Sublingual Film, get emergency help or call 911 right away. Tell your healthcare provider if you are living in a household where there are small children.

SUBOXONE Sublingual Film contains an opioid medicine called buprenorphine that can cause serious and life-threatening breathing problems, especially if you take or use certain other medicines or drugs.

Talk to your healthcare provider about naloxone, a medicine available to patients for emergency treatment of an opioid overdose, including accidental use of SUBOXONE Sublingual Film by a child. If naloxone is given, you must call 911 or get emergency medical help right away to treat an overdose or accidental use of an opioid.

SUBOXONE Sublingual Film can cause serious and life‐threatening breathing problems. Get emergency help right away if you:

Do not take SUBOXONE Sublingual Film with certain medicines. Taking SUBOXONE Sublingual Film with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, decreased awareness, breathing problems, coma, and death.

Do not inject (“shoot-up”) SUBOXONE Sublingual Film. Injecting SUBOXONE Sublingual Film may cause life-threatening infections and other serious health problems. Injecting SUBOXONE Sublingual Film may cause sudden serious withdrawal symptoms such as pain, cramps, vomiting, diarrhea, anxiety, sleep problems, and cravings.

Do not switch from SUBOXONE Sublingual Film to other medicines that contain buprenorphine without talking with your healthcare provider. The amount of buprenorphine in a dose of SUBOXONE Sublingual Film is not the same as in other medicines that contain buprenorphine. Your healthcare provider will prescribe a starting dose of SUBOXONE Sublingual Film that may be different than other buprenorphine containing medicines you may have been taking.

Do not stop taking SUBOXONE Sublingual Film suddenly. You could become sick and have withdrawal symptoms because your body has become used to the medicine (physical dependence). Physical dependence is not the same as drug addiction.

In an emergency, have family members tell emergency department staff that you are physically dependent on an opioid and are being treated with SUBOXONE Sublingual Film.

Never give anyone else your SUBOXONE Sublingual Film. They could die from taking it. Selling or giving away SUBOXONE Sublingual Film is against the law.

Death has been reported in those who are not opioid dependent.

Who should not take SUBOXONE Sublingual Film?

Do not take SUBOXONE Sublingual Film if you are allergic to buprenorphine or naloxone.

Do not take SUBOXONE Sublingual Film before the effects of other opioids (e.g., heroin, hydrocodone, methadone, morphine, oxycodone) have started to wear off as you may experience withdrawal symptoms.

Before taking SUBOXONE Sublingual Film, tell your healthcare provider about all of your medical conditions, including if you have:

Tell your healthcare provider if you are:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What should I avoid while taking SUBOXONE Sublingual Film?

What are the possible side effects of SUBOXONE Sublingual Film?

These are not all the possible side effects. Call your healthcare provider for medical advice about side effects.

To report pregnancy or side effects associated with taking SUBOXONE Sublingual Film, please call 1-877-782-6966. You are encouraged to report negative side effects of drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information about SUBOXONE Sublingual Film, see the full Prescribing Information, and Medication Guide or talk to your healthcare provider. For REMS information visit www.suboxoneREMS.com.