Home Page: Seminars in Fetal and Neonatal Medicine

Time 2021-05-27 15:12:00

Web Name: Home Page: Seminars in Fetal and Neonatal Medicine

WebSite: http://www.sfnmjournal.com

ID:179486

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Few areas of medicine have had as much success as newborn care, one of the younger pediatric subspecialties. The term “neonatology” was only introduced in the 1960's when the majority of preterm infants died soon after birth, mostly from respiratory failure. More View Seminars in Fetal and Neonatal Medicine's full List of Topics here. Vol. 26:2 Therapeutic drift in newborn care Ju Lee Oei, Richard J. Martin Vol. 26:1 Quality Improvement John Zupancic Vol. 25:6 Caffeine Barbara Schmidt Vol. 25:5 Perinatal Perfusion Samir Gupta, Maged Costantine, Steven Donn Vol. 25:4 FIRS (Fetal Inflammatory Response Syndrome) Thomas E Wiswell, Steven M. Donn Vol. 25:3 Long term outcomes following very preterm birth Neil Marlow, Samantha J Johnson Vol. 25:2 Oxygen in the Neonatal Period Maximo Vento Torres, Christian Poets Vol. 25:1 Bone metabolic disorders in premature and full term neonates Charalampos Dokos Vol. 24:6 Delivery Room Emergencies Eduardo Bancalari Vol. 24:5 Chronic Ventilator Dependence in Infants Joseph Piccione, Alexiou Stamatia Vol. 24:4 Pain Management in the Neonate Elaine Boyle Vol. 24:3 Antenatal and Postnatal Corticosteroids to Improve Outcomes in Newborn Infants B Manley, C McKinlay Translational insights into mechanisms and preventive strategies after renal injury in neonatesJenny Voggel, Jasmine Mohr, Kai-Dietrich Nüsken, Jörg Dötsch, Eva Nüsken, Miguel A. Alejandre AlcazarDOI: https://doi.org/10.1016/j.siny.2021.101245Publication stage: In Press Corrected ProofPreviewFull-Text HTMLPDFxAdverse perinatal circumstances can cause acute kidney injury (AKI) and contribute to chronic kidney disease (CKD). Accumulating evidence indicate that a wide spectrum of perinatal conditions interferes with normal kidney development and ultimately leads to aberrant kidney structure and function later in life. The present review addresses the lack of mechanistic knowledge with regard to perinatal origins of CKD and provides a comprehensive overview of pre- and peri-natal insults, including genetic predisposition, suboptimal nutritional supply, obesity and maternal metabolic disorders as well as placental insufficiency leading to intrauterine growth restriction (IUGR), prematurity, infections, inflammatory processes, and the need for life-saving treatments (e.g.Insights into the mechanisms of alveolarization - Implications for lung regeneration and cell therapiesMaria Hurskainen, Chanèle Cyr-Depauw, Bernard ThébaudDOI: https://doi.org/10.1016/j.siny.2021.101243Publication stage: In Press Corrected ProofPreviewFull-Text HTMLPDFxAlthough the lung has extensive regenerative capacity, some diseases affecting the distal lung result in irreversible loss of pulmonary alveoli. Hitherto, treatments are supportive and do not specifically target tissue repair. Regenerative medicine offers prospects to promote lung repair and regeneration. The neonatal lung may be particularly receptive, because of its growth potential, compared to the adult lung. Based on our current understanding of neonatal lung injury, the ideal therapeutic approach includes mitigation of inflammation and fibrosis, and induction of regenerative signals.The neonatal liver: Normal development and response to injury and diseaseNaoki TanimizuDOI: https://doi.org/10.1016/j.siny.2021.101229Publication stage: In Press Corrected ProofPreviewFull-Text HTMLPDFxThe liver emerges from the ventral foregut endoderm around 3 weeks in human and 1 week in mice after fertilization. The fetal liver works as a hematopoietic organ and then develops functions required for performing various metabolic reactions in late fetal and neonatal periods. In parallel with functional differentiation, the liver establishes three dimensional tissue structures. In particular, establishment of the bile excretion system consisting of bile canaliculi of hepatocytes and bile ducts of cholangiocytes is critical to maintain healthy tissue status.Tissue engineering: Relevance to neonatal congenital heart diseaseKevin M. Blum, Gabriel J.M. Mirhaidari, Christopher K. BreuerDOI: https://doi.org/10.1016/j.siny.2021.101225Publication stage: In Press Corrected ProofPreviewFull-Text HTMLPDFxCongenital heart disease (CHD) represents a large clinical burden, representing the most common cause of birth defect-related death in the newborn. The mainstay of treatment for CHD remains palliative surgery using prosthetic vascular grafts and valves. These devices have limited effectiveness in pediatric patients due to thrombosis, infection, limited endothelialization, and a lack of growth potential. Tissue engineering has shown promise in providing new solutions for pediatric CHD patients through the development of tissue engineered vascular grafts, heart patches, and heart valves.Recovery of the brain after intraventricular hemorrhageBokun Cheng, Praveen BallabhDOI: https://doi.org/10.1016/j.siny.2021.101224Publication stage: In Press Corrected ProofPreviewFull-Text HTMLPDFxIntraventricular hemorrhage (IVH) remains a major complication of prematurity, worldwide. The severity of IVH is variable, ranging from a tiny germinal matrix bleed to a moderate-to-large ventricular hemorrhage or periventricular hemorrhagic infarction. Survivors with IVH often suffer from hydrocephalus and white matter injury. There is no tangible treatment to prevent post-hemorrhagic cerebral palsy, cognitive deficits, or hydrocephalus in these infants. White matter injury is attributed to blood-induced damage to axons and maturing oligodendrocyte precursors, resulting in reduced myelination and axonal loss. About Seminars in Fetal and Neonatal Medicine Seminars in Fetal and Neonatal Medicine (formerly Seminars in Neonatology) is a bi-monthly journal which publishes topic-based issues, including current 'Hot Topics' on the latest advances in fetal and neonatal medicine. The change in title relates to the growing interest amongst obstetricians, midwives and fetal medicine specialists.The Journal commissions review-based content covering current clinical opinion on the care and treatment of the neonate and draws on the necessary specialist knowledge, including that of the respiratory physician, the infectious disease physician, the surgeon, as well as the paediatrician and obstetrician. Access this journal on ScienceDirect Visit ScienceDirect to see if you have access via your institution. Journal Access Full-text articles are available from 1996 to the present. Access to abstracts is complimentary. Access to full text is limited to personal subscribers. Activate Online Access We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.

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