Home Page: Mayo Clinic Proceedings

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SPECIAL ARTICLEInfusion of Anti-Spike Monoclonal Antibodies to High-Risk Patients with Mild to Moderate COVID-19 Best practices include multidisciplinary team evaluation, effective leveraging of clinical trials and available treatments, deployment of remote monitoring tools, and maintenance of adequate operating capacity to not require surge adjustments. [Watch video]ORIGINAL ARTICLE Prevalence of SARS-CoV-2 Antibodies in a Multistate Academic Medical Center Does community prevalence and disease burden influence the seroprevalence of health care personnel despite personal protective equipment use in the workplace? [Watch video]REVIEW The Effect of Convalescent Plasma Therapy on COVID-19 Patient Mortality This review and analysis examines the mortality rate of transfused COVID-19 patients and suggests early transfusion of high-titer plasma represents the optimal use scenario. ORIGINAL ARTICLELower Extremity Arterial Disease Predicts Incident Atrial Fibrillation Atrial fibrillation is independently associated with ischemic stroke, indicating that cardio-embolic phenomenon may play a role in the pathophysiology of stroke in patients with peripheral arterial disease. [Watch video]Dr Sandeep Pagali notes the Automated Mayo Delirium Prediction tool appears to be a reliable automated tool for delirium risk prediction with hospitalization.Read the article, Predicting Delirium Risk Using an Automated Mayo Delirium Prediction Tool Development and Validation of a Risk Stratification Model Dr Raymund Razonable describes the details and processes used in developing a model of care for safe and efficient outpatient spike monoclonal antibody infusions that significantly reduces COVID-19-related hospitalization and death.Read the article, A Framework for Outpatient Infusion of Anti-Spike Monoclonal Antibodies to High-Risk Patients With Mild to Moderate Coronavirus Disease-19: The Mayo Clinic ModelDr Mohamad Bydon reports the results of the first 400 screw placements with robotic spinal surgery at Mayo Clinic.Read the article, Initiation of a Robotic Program in Spinal Surgery: Experience at a Three-Site Medical CenterDr Cody Nesvick finds the biological effective dose is associated with likelihood of obliteration following single-session stereotactic radiosurgery for arteriovenous malformations.Read the article, The Role of Biological Effective Dose in Predicting Obliteration After Stereotactic Radiosurgery of Cerebral Arteriovenous MalformationsDr Rickey Carter and Dr Elitza Theel found very low seroprevalence rates for SARS-CoV-2 antibodies in a multi-state population, indicating the safety protocols for masking, handwashing, and social distancing were effective in reducing spread of infection.Read the article, Prevalence of SARS-CoV-2 Antibodies in a Multistate Academic Medical CenterDr Michael O'Rourke shares comprehensive recommendations for optimization of pain medicine in perioperative medicine.Read the article, Preoperative Management of Opioid and Nonopioid Analgesics: Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus StatementDr Michelle Hill and Dr Ellen McPhail note unequivocal identification of the amyloid type is mandatory for optimal treatment of patients with systemic amyloidosis.Read the article, The Clinical Impact of Proteomics in Amyloid TypingDr Bhanuprakash Kolla examines the common causes, shares algorithms for diagnosis, and offers treatment options for patients who experience excessive daytime sleepiness.Read the article, Excessive Daytime Sleepiness: A Clinical ReviewDr John O'Horo and Dr Andrew Badley identify 3 key components for mitigating the spread of disease: acquired immunity, public health interventions, and treatment as prevention.Read the article, A Blueprint to Control the SARS-CoV-2 PandemicDr Robert McBane finds better outcomes are achieved in patients treated with anticoagulation for calf vein thrombosis.Read the article, Calf Vein Thrombosis Outcomes Comparing Anticoagulation and Serial Ultrasound Imaging Management StrategiesDr Matthew Ziegelmann notes no difference in the number of refills requested in the period after implementation of reduced opioid prescribing rates.Read the article, Prescribing After Implementation of Standardized Postoperative Opioid Prescribing Guidelines: An Interrupted Time Series AnalysisMs Theodora Oikonomidi finds remote digital diabetes monitoring can be intrusive and may add practical/psychosocial burdens, loss of control, data safety/misuse, and dehumanization of care.Read the article, An International, Mixed-Methods Study of the Perceived Intrusiveness of Remote Digital Diabetes MonitoringDr Andrew Tseng and Dr Fadi Shamoun find a relationship between abnormal ankle-brachial index testing results and atrial fibrillation.Read the article, Lower Extremity Arterial Disease as a Predictor of Incident Atrial Fibrillation and Clinical OutcomesDr Elizabeth Stephens and Dr M. Yasir Qureshi review exciting developments in fetal cardiac interventions for improving outcomes in such conditions as hypoplastic left heart syndrome and Ebstein anomaly.Read the article, Towards Eliminating Perinatal Comfort Care for Prenatally-Diagnosed Severe Congenital Heart Defects: A VisionDr Lin Yee Chen finds that in community-dwelling older adults without atrial fibrillation, frequent premature atrial contractions were associated with poorer cognitive function and higher prevalence of dementia or mild cognitive impairment.Read the article, Frequent Premature Atrial Contractions are Associated With Poorer Cognitive Function in the Atherosclerosis Risk in CommunitiesDr.Vibhu Parcha looked at the past 20-year trends for cardiovascular disease in 11 southern states sometimes referred to as the stroke-belt, because of its high incidents of stroke and cardiovascular disease.Read the article, Geographic Inequalities in CV Mortality in the US: 1999-2018MCP: 60 Seconds content contains abbreviated clips extracted from the full-length author interview videos and is intended to give a quick sampling of the video message. Links to the full-length video and related article are available in the individual video clip descriptions.See MCP 60 clips Listen to the highlights and interviews from the May 2021 issue. A new episode premieres each week, so check back often to hear the latest podcast! Dr. R. Scott Wright, a Professor of Medicine in Cardiology facilitates a conversation with Dr. David R. Holmes, Jr. MD, a Distinguished Professor of Medicine in Cardiology, both at Mayo Clinic in Rochester, Minnesota. They reminisce about past challenges and review current and future state of the art treatments emanating from the interventional cath lab, and offer hope for future patients. They touch on the invention of the Watchman device, the evolution of TAVR, and recommend maintaining a sense of wonder.Featuring Dr Carlo Brugnara, a Professor of Pathology from Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, interviewed by our Associate Editor, Dr Vincent Rajkumar.Dr Vesna Garovic, Section Editor for Women's Health and Medicine of Sex Differences, facilitates a conversation with Dr Nanette Wenger, a distinguished professor from Emory University in Atlanta, Georgia.Additional VideosDr. Nanette Wenger on Women's Heart StatementNanette Wenger: History of Cardiology at Emory and GradyDr P. James B. Dyck facilitates a conversation with a scholar in Pioneers and Legends in Medicine with his father, Dr Peter J. Dyck.Dr Karl Nath facilitates a conversation with a scholar in Pioneers and Legends in Medicine. Watch the feature with Dr Donald Scholz.Dr Karl Nath is delighted to invite you to view this brief conversation with Dr Robert Kyle in the series Pioneers and Legends in Medicine.Mayo Clinic College of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Access this journal on ScienceDirect Visit ScienceDirect to see if you have access via your institution.Dr Karl Nath discusses the Editor's Choice and Highlighted articles in the May 2021 issue. Download MP3Philip A. Ades, MD, FACCProfessor of Medicine and Medical Director of Cardiac Rehabilitation, Division of Cardiology, University of Vermont College of Medicine, South Burlington, Vermont Mayo Clinic Resources Find resources that Mayo Clinic offers to healthcare professionals and the public to address their health needs and promote the science of medicine. We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.

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