Sucraid® (sacrosidase) Oral Solution - Patient Information
Time 2022-09-19 18:13:01Web Name: Sucraid® (sacrosidase) Oral Solution - Patient Information
WebSite: http://www.sucraid.com
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Prescribing Information Healthcare Provider SiteImportant Safety Information for Sucraid® (sacrosidase) Oral Solution
Sucraid® may cause a serious allergic reaction. If you notice any swelling or have difficulty breathing, get emergency help right away. Sucraid® does not break down some sugars that come from the digestion of starch. You may need to restrict the amount of starch in your diet. Your doctor will tell you if you should restrict starch in your diet. Tell your doctor if you are allergic to, have ever had a reaction to, or have ever had difficulty taking yeast, yeast products, papain, or glycerin (glycerol). Tell your doctor if you have diabetes, as your blood glucose levels may change if you begin taking Sucraid®. Your doctor will tell you if your diet or diabetes medicines need to be changed. Some patients treated with Sucraid® may have worse abdominal pain, vomiting, nausea, or diarrhea. Constipation, difficulty sleeping, headache, nervousness, and dehydration have also occurred in patients treated with Sucraid®. Check with your doctor if you notice these or other side effects. Sucraid® has not been tested to see if it works in patients with secondary (acquired) sucrase deficiency. NEVER HEAT SUCRAID® OR PUT IT IN WARM OR HOT BEVERAGES OR INFANT FORMULA. Do not mix Sucraid® with fruit juice or take it with fruit juice. Take Sucraid® as prescribed by your doctor. Normally, half the dose of Sucraid® is taken before a meal or snack and the other half is taken during the meal or snack. Sucraid® should be refrigerated at 36°F-46°F (2°C-8°C) and should be protected from heat and light.You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.
Indication
Sucraid® (sacrosidase) Oral Solution is an enzyme replacement therapy for the treatment of genetically determined sucrase deficiency, which is part of Congenital Sucrase-Isomaltase Deficiency (CSID).
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IMPORTANT SAFETY INFORMATION:
If you’re suffering from Congenital Sucrase-Isomaltase Deficiency (CSID), ask your doctor if Sucraid® (sacrosidase) Oral Solution is right for you.
HOW TO ORDER HOW TO ORDERIMPORTANT SAFETY INFORMATION:
If you’re suffering from Congenital Sucrase-Isomaltase Deficiency (CSID), ask your doctor if Sucraid® (sacrosidase) Oral Solution is right for you. How To Order If you’re suffering from Congenital Sucrase-Isomaltase Deficiency (CSID), ask your doctor if Sucraid® (sacrosidase) Oral Solution is right for you.About Sucraid®
Sucraid® is the only FDA-approved enzyme replacement therapy for the treatment of CSID.
Learn MoreAbout CSID
Congenital Sucrase-Isomaltase Deficiency (CSID), also known as Genetic Sucrase-Isomaltase Deficiency (GSID).
Learn MorePatient Assistance
SucraidASSIST™ is a comprehensive support program that provides information and support.
Learn MorePatient Stories
Testimonials from Sucraid® patients.
Learn MoreWhat is Congenital Sucrase-Isomaltase Deficiency?
CSID is a disorder that reduces the effectiveness of enzymes that digest carbohydrates (sugar and starch). Congenital Sucrase-Isomaltase Deficiency, also known as Genetic Sucrase-Isomaltase Deficiency (GSID), is an inherited disorder that causes these digestive enzymes either to be missing or to not work as well.
Download a CSID Doctor Discussion Guide
Talking to your doctor about your CSID symptoms — especially when they involve bloating, gassiness, and diarrhea — might seem embarrassing. But sharing these details and your medical history helps your doctor make a diagnosis.
Just as your doctor has questions for you, it’s natural for you to have questions for your doctor. Using a tool like the CSID Doctor Discussion Guide helps you organize your personal information and any questions you may have so that you are prepared for your appointment.
Just click on the bar below and download the discussion guide, fill it out, and share the information with your doctor during your next visit.
Enter your email so that we may keep you up to date with the latest information about disease and drug therapy.
Download a CSID Doctor Discussion Guide
Talking to your doctor about your CSID symptoms — especially when they involve bloating, gassiness, and diarrhea — might seem embarrassing. But sharing these details and your medical history helps your doctor make a diagnosis.
Just as your doctor has questions for you, it’s natural for you to have questions for your doctor. Using a tool like the CSID Doctor Discussion Guide helps you organize your personal information and any questions you may have so that you are prepared for your appointment.
Just click on the bar below and download the discussion guide, fill it out, and share the information with your doctor during your next visit.
Enter your email so that we may keep you up to date with the latest information about disease and drug therapy.
See how Sucraid® works. Watch the Video
What is Sucraid®?
Sucraid® is an FDA-approved drug for the treatment of genetically determined sucrase deficiency, which is part of Congenital Sucrase-Isomaltase Deficiency (CSID). Sucraid® is an enzyme replacement therapy, providing a substitute for the sucrase enzyme in the small intestine that is missing or not working in people who have CSID. CSID may also be called Sucrose Intolerance, carbohydrate maldigestion or intolerance or Genetic Sucrase-Isomaltase Deficiency (GSID).
About Sucraid® Single-Use Container 81Complete Resolution
Patients who became asymptomatic* with Sucraid® in clinical trials.1
*Patients who took Sucraid® with each meal were considered asymptomatic if they reported no GI symptoms for at least 7 of the 10 study days. 1 Treem WR, McAdams L, Standford L, Kastoff G, Justinich C, Hyams J. Sacrosidase Therapy for Congenital Sucrase-Isomaltase Deficiency. J Pediatr Gastroenterol Nutr. 1999;28(2):137-42.
81Complete Resolution
Patients who became asymptomatic* with Sucraid® in clinical trials.1
*Patients who took Sucraid® with each meal were considered asymptomatic if they reported no GI symptoms for at least 7 of the 10 study days. 1 Treem WR, McAdams L, Standford L, Kastoff G, Justinich C, Hyams J. Sacrosidase Therapy for Congenital Sucrase-Isomaltase Deficiency. J Pediatr Gastroenterol Nutr. 1999;28(2):137-42.
How to Get Sucraid®
SPECIALTY PHARMACY
Sucraid® is a drug that is only available by prescription, but a prescription for Sucraid® cannot be filled by your corner drugstore. The only way to get a Sucraid® prescription filled is through the specialty pharmacy. Call the specialty pharmacy at 1-833-800-0122.
Trial Therapy
If your doctor has prescribed Sucraid® for you, it is either because you have been diagnosed with a sucrase-isomaltase enzyme deficiency or because your doctor suspects the reason why you have frequent GI symptoms is because the sucrase-isomaltase enzymes in your small intestine are not working. If that is the case, your doctor wishes to determine if a trial of Sucraid® therapy would help relieve some of your GI symptoms.
Here’s What You Get
Sucraid® comes in a translucent plastic bottle containing approximately 118 mL of concentrated solution, packaged with two bottles per boxEach mL of solution contains 8,500 international units (IU) of sacrosidaseA 1-mL measuring scoop is provided with each box How To OrderPatient Stories
See Patient VideosFor us, Sucraid® is the difference between strict diet adherence and a more normal diet. Sucraid® means more freedom of choice for us.”
Aileen, Caregiver for Patient Treated With Sucraid®
Insights
An enzyme is a naturally-occurring protein that makes the chemical reactions that occur all the time in the body, occur much faster.
We rely on the enzymes our body produces to help the tissues and organs in our body function normally. Sucrase is the enzyme that helps our body digest sucrose, which is a fancy name for white table sugar.
Sucrose is a complex sugar called a disaccharide, created by the combination of two simple sugars (monosaccharides), glucose and fructose.
Sucrose is mainly found in plants and is the primary component of most granulated sugars we use in baking. It’s commonly known as white table sugar and/or brown sugar, or just sugar. These sugars are mostly refined from sugar beets or sugar cane. Today, sucrose can be found in a range of commercially prepared foods like cookies, ice cream, candy, crackers, and cured meats. Sucrose is also found naturally in many fresh fruits.
Sucraid facilitates the breakdown of the complex sugar (sucrose) into its simpler forms, enabling the absorption of the simple sugars from the small intestine into the bloodstream where it can be used by the tissues and organs in the body as a source of energy. In clinical studies of CSID patients, sacrosidase, the active ingredient in Sucraid, was shown to provide significant relief for most patients of the gastrointestinal (GI) symptoms associated with CSID. Sucraid can help affected individuals maintain a more normal diet that can include foods that contain sucrose.
Scientific words sometimes use the same ending to identify various compounds that all belong to the same, specific category.
For example, the names for various sugars all end in “ose,” such as glucose, fructose, lactose, and sucrose. The names for various enzymes often begin with the name for the compound they affect and all end in “ase,” such as lactase, which breaks down lactose; protease, which breaks down proteins; lipase, which breaks down lipids (fats); and sucrase, which breaks down sucrose.
Carbohydrates are one of the three main sources of nutrients in our diets.
The other two are proteins and lipids (fats). Carbohydrates are made by plants to store energy. They are complex compounds that must be broken down to a simpler form before they can be absorbed into the bloodstream.
There are three types of carbohydrates. Sugars are simple or complex carbohydrates, found in white table sugar, baked goods, fruits, vegetables, and dairy products. Starches are made up of more than one sugar unit bound together and are found in whole grains, potatoes, pasta, vegetables, and beans. Dietary fiber is a very complex carbohydrate that your body cannot digest, so it passes through the intestine undigested. Fiber is a food source for the “good” bacteria that exist naturally in your large intestine. Fiber is present in fruits, vegetables, legumes, nuts, seeds, and whole grains.
If you think you may have CSID, it is recommended that you schedule a visit to discuss your concerns with a gastroenterologist.
Watch Now
Behind the Mystery: Rare & Genetic Diseases is a special video on the balancing act of treating individuals who have CSID. This is an interview with Dr. William Treem, a pediatric gastroenterologist who has studied and treated patients with CSID for years.
QOL Medical contributed financially to the production and air time of this video, which appeared on the Lifetime Television Network. Dr. William Treem, who appears in this video, was a paid consultant of QOL Medical and was compensated for his time participating in this video. Please see the indication and important safety information for Sucraid® below.
Important Safety Information for Sucraid® (sacrosidase) Oral Solution
Sucraid® may cause a serious allergic reaction. If you notice any swelling or have difficulty breathing, get emergency help right away.Sucraid® does not break down some sugars that come from the digestion of starch. You may need to restrict the amount of starch in your diet. Your doctor will tell you if you should restrict starch in your diet.Tell your doctor if you are allergic to, have ever had a reaction to, or have ever had difficulty taking yeast, yeast products, papain, or glycerin (glycerol).Tell your doctor if you have diabetes, as your blood glucose levels may change if you begin taking Sucraid®. Your doctor will tell you if your diet or diabetes medicines need to be changed.Some patients treated with Sucraid® may have worse abdominal pain, vomiting, nausea, or diarrhea. Constipation, difficulty sleeping, headache, nervousness, and dehydration have also occurred in patients treated with Sucraid®. Check with your doctor if you notice these or other side effects.Sucraid® has not been tested to see if it works in patients with secondary (acquired) sucrase deficiency.NEVER HEAT SUCRAID® OR PUT IT IN WARM OR HOT BEVERAGES OR INFANT FORMULA. Do not mix Sucraid® with fruit juice or take it with fruit juice. Take Sucraid® as prescribed by your doctor. Normally, half the dose of Sucraid® is taken before a meal or snack and the other half is taken during the meal or snack.Sucraid® should be refrigerated at 36°F-46°F (2°C-8°C) and should be protected from heat and light.You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.
Indication
Sucraid® (sacrosidase) Oral Solution is an enzyme replacement therapy for the treatment of genetically determined sucrase deficiency, which is part of Congenital Sucrase-Isomaltase Deficiency (CSID).
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