BioTek Instruments

Time 2020-09-17 04:02:48

Web Name: BioTek Instruments

WebSite: http://www.biotek.com

ID:49395

Keywords:

BioTek,Instruments,biotekinstrumentation,lifescienceinstrumentation,detection,li

Description:

Multi-Mode Detection TechnologiesAbsorbanceAlpha DetectionFiltered LuminescenceFlash LuminescenceFluorescence IntensityFluorescence PolarizationGlow LuminescenceTime Resolved FluorescenceTR-FRETImager Microplate Reader Technologies4-Zone Incubation and Condensation ControlAugmented MicroscopyHybrid TechnologyLaser AutofocusPeltier Cooling ModuleVariable Bandwidth MonochromatorsLiquid Handling TechnologiesAutomated, Gentle Media ExchangeDual-Action ManifoldParallel DispenseRandom Access DispenseUltrasonic AdvantageVerify TechnologyRequest QuoteClick here to request a quote on a product, software, peripheral or service contract.PeripheralsPeripheralsBioTek s peripheral products help to expand your BioTek instrument applications and improve workflow efficiency. From gas controllers to micro-volume plates, we have the peripherals to help advance your research.AccessoriesTo complete or enhance your BioTek imager, microplate reader, liquid handling or robotics system, we offer a wide range of accessories, from tubing and bottles to imaging filter cubes. Search our Accessory database for Accessories compatible with your instrument. Search by Keyword, Part #, Product or Accessory Type.Application Starter Kits BioTek s Application Starter kits contain everything you ll need to implement the latest assays for a particular application, quickly and with minimal training. Kits contain hardware, software, consumables and reagents all in a convenient kit.ApplicationsCell Culture QCAutomated imaging tools can provide valuable information for improving routine cell culturing techniques and increasing the effectiveness and reproducibility of downstream cell-based assays. Conventional methods for evaluating cell culturing techniques and assay design consist of manual inspection of a small subset of the cell population at random locations and time points.Cell Health and ViabilityCell health and viability measurements provide essential insight into a broad range of biological processes and treatment responses. Diverse assay formats and reagents have been developed that measure specific aspects of cell viability corresponding to particular cellular response pathways and mechanisms of injury.Cell MetabolismCellular metabolism comprises a number of biochemical reactions that occur in concert within the cells of living organisms. These orchestrated reactions, better described as metabolic pathways allow organisms to function and respond to environmental changes. Agilent cell metabolism assays detect discrete changes in cell bioenergetics in real time, providing a window into the critical functions that provide ATP, the energy that cells need for activation, signaling, proliferation, and biosynthesis.Cell Migration and InvasionCell migration and invasion are live cell kinetic assays useful in oncology research. The principle difference between migration and invasion is that migration refers to normal cell movement; whereas invasion describes cells actively invading surrounding tissue. It can do this under the influence of a chemoattractant gradient and secretion of proteases. There are numerous methods for performing these assays including scratch assays performed on a monolayer of cells adhered to plasticware (microplates or culture inserts) or using 3D cell culture models.Developmental BiologyA macro trend in drug discovery is the use of complex models of disease early in preclinical studies. An approach following this viewpoint is the use of whole organism models involving living invertebrates and vertebrates such as nematodes and zebrafish conducive to drug screening methods.Histology and Slide ScanningHistology is typically performed on fixed tissue samples using upright microscopes equipped with oculars. Cytation and Lionheart FX provide automated digital imaging of these samples using color brightfield microscopy. Low to high magnifications from 1.25x to 60x (100x with Lionheart FX) can be combined with Cytation Gen5 image processing features such as image stitching to increase field of view.ImmunologyThe immune system relies on diverse mechanisms working in concert to defend the host from infection and to identify and remove aberrant or damaged cells. Dysregulation of the immune system can lead to a variety of disease conditions, including autoimmune disorders, allergies, and cancer. Additionally, the immune system is a critical consideration for vaccine development and cell, tissue and organ transplants.Immuno-OncologyWhile harnessing the patient s immune system to fight cancer is not a new concept, there have been significant strides in the past decade to more effectively direct and activate components of the immune system and counter the measures certain tumors adopt to shield itself from immune attack. These include immunotherapeutic drugs based on directing immune cells to tumors based on specific antigens they present, PD-1 checkpoint inhibition and the ex vivo manipulation of the patient s own immune cells to better drive an immune response to cancer.MicrobiologySince the advent of a lens system that enabled the visualization of bacteria and protists in 1671, the microscope remains a ubiquitous tool for the scientific study of live and fixed microorganisms. Investigating the structure, function, and typing of the highly diverse array of microorganisms spans heterogeneous applications including, but not limited to, the elucidation, diagnosis, and treatment of human and plant disease, food and water safety testing, vaccine development, investigation and production of industrial lipases, protein transfection to mammalian cells, environmental health and impact appraisal, horticultural and agricultural soil assessment, and exploration of alternative fuel sources.Molecular Biology and BiochemicalBiochemical assays run the gamut from routine ELISAs to micro-volume nucleic acid and protein quantification. Endpoint and kinetic, single- and multi-wavelength assays are essential experimental tools. BioTek s multi-mode readers have the flexibility to accommodate a very broad range of applications with superior performance.Rapid Cell SignalingG-protein coupled, seven-transmembrane (7-TM) receptors (GPCRs) represent large, diverse gene families found in fungi, plants and animals. The GPCR family of receptors is involved primarily with internalizing extracellular environmental signals via interaction with intracellular G-proteins. GPCR ligands and modulators range from peptide and non-peptide molecules to chemokines, nucleosides, growth factors and light.Stem Cell ResearchResearch into the reprogramming of somatic cells into pluripotent stem cells received the Nobel Prize in 2012. The long term importance of this research resides in the use of stem cells for regenerative therapies; for the short term, however these cells represent a potential unlimited source of highly physiologically relevant cells, akin to human primary cells, that can be used as drug discovery reagents.VirologyResearch into the diverse aspects of virology are made possible by a broad range of applications and assay formats, from relatively simple methods for viral detection to those designed to elucidate complex immune responses and pathological processes. BioTek instruments provide versatile platforms for conducting viral research, with optimized imaging- and plate reader-based solutions, as well as liquid handling and automation tools for increased assay throughput and reproducibility.ResourcesApplication NotesBioTek s application notes present the latest-breaking scientific content covering the vast range of applications across our entire product line. Browse applications by topic, detection and product or use the simple keyword search to find the application notes that will facilitate your research.Application BulletinsBioTek s application bulletins provide brief, concise descriptions of timely applications enabled with BioTek instrumentation.Application GuidesMany applications are straightforward and need no explanation, but best practices and tips tricks are useful for many complex or esoteric workflows. BioTek s application guides offer detailed information on a variety of topics.Scientific PublicationsSearch or browse our database to find scientific articles submitted by BioTek s applications scientists and published in leading journals.Scientific PostersBioTek s application team has developed more than 170 scientific posters on their latest research highlighting the applications enabled with our life science instrumentation. Browse or search the topics or products of interest.Technical NotesOur Technical Notes illustrate product-specific capabilities and common applications for BioTek microplate instrumentation, and their implementation in common experimental design.Visual AbstractsBioTek s Visual Abstracts are brief, animated presentations that describe the workflow of a single specific application. Imaging microscopy-focused Visual Abstracts explain the Augmented Microscopy workflow for a wide range of assays, with key capture process analyze publish concepts presented. Other Visual Abstracts describe the utility of BioTek s liquid handling and multi-mode instruments in a variety of applications. Check back often for our latest additions to the Visual Abstract library!White PapersBrowse BioTek s white papers for timely information on such important topics as Reactive Oxygen Species and 3D Cell culture.CitationsSearch the more than 4,000 scientific citations for BioTek s products within our database to learn more about the applications for our life science instrumentation as they re used around the world.VideosHere you will find a collection of videos found throughout our site. These videos can also be found on BioTek s YouTube channel.WebinarsWebinars UpcomingWebinars ArchivedOur webinar archives are available for on-demand viewing- search to find a topic, application or product of interest. You can also register to be invited to future webinars here.Service SupportSales Support OfficesBioTek s highly trained sales and service professionals are experts in life science instrumentation. They will guide you through your decision process and help you select the proper equipment for your application, assist with installation in your lab, and train your staff on the use of the instrumentation.Field Applications ScientistsBioTek Field Applications Scientists (FAS) and Product Specialists provide unparalleled scientific support, assisting with experimental planning and assay optimization on BioTek s instrumentation and software.Technical SupportThe BioTek Global Technical Support Center (GTS) is your Help Desk for all questions related to BioTek product use, maintenance, troubleshooting support and other frequently asked questions. Normal GTS hours are weekdays from 8:30 A.M. - 5:30 P.M Eastern Standard Time, excluding holidays.Global ServiceBioTek Instrument Service and Repair is available worldwide at several of our International Service Centers. Field Service is also available for many customers throughout the world.FAQ DiscussionsSearch our frequently asked questions and discussion groups for imaging microscopy, detection, liquid handling, robotics and software.Customer Resource CenterAccess BioTek s Customer Resource Center to search frequently asked questions and discussion groups for imaging microscopy, detection, liquid handling, robotics and software. If you re already a customer, login for full access to participate in peer-to-peer discussions, download user manuals and software, and view order or product information specific to you! To register for the first time, click Login and Not a Member to sign up and receive instant access. Having trouble? Watch this quick registration tutorial.Request SupportUse this form to ask us a quick question or request support. For immediate help, visit our Customer Resource Center to search FAQ s and discussions.Contact UsContact BioTek today. Ask a sales or technical question or request service.About UsNews Synergy H1’s Continuously Variable Bandwidth Monochromators Optimize Assay Performance July 2, 2020 - BioTek Instruments announces the availability of variable bandwidth monochromators on their modular and versatile Synergy™ H1 Hybrid Multi-Mode Reader. This allows researchers to achieve even greater levels of assay sensitivity and specificity compared to fixed bandwidth systems. Read more LogPhase 600 Microbiology Reader Measures Microbial Growth Curves in Multiple Microplates June 9, 2020 - BioTek unveils a unique class of microplate readers with the new LogPhase 600 Microbiology Reader. The LogPhase 600 is the only four-plate microplate reader purpose-built to perform microbial growth curve analysis. Multiple plate measurements increase throughput and reduce the need for multiple costly single-plate absorbance readers that take up valuable bench space. At the same time, highly consistent environmental conditions support high quality absorbance results without growth curve artifacts, even in bacterial and yeast assays with extended incubation periods. Read more Agilent’s BenchCel Microplate Handler Now Available through BioTek for Full Workflow Automation May 28, 2020 - BioTek announces that Agilent’s BenchCel Microplate Handler is now added to its portfolio of walkaway automated solutions. The modular BenchCel Microplate Handler is a high-speed robot with an open, flexible and scalable format to bring efficiency to diverse applications such as ELISA, endpoint add-and-read assays and cell fix-stain-image processes. Read moreMORE NEWSEvents MORE eventsCustomer SpotlightsWe are dedicated to developing and supporting instrumentation that enables a broad range of applications for scientists around the world. We can tell you about how BioTek instrumentation can benefit your research, but we d rather you hear it directly from our customers! Browse the Customer Spotlights below to see how BioTek is helping to make their research possible.AwardsSee some of the many awards that BioTek and our products have received over the years.HistoryBioTek is a family-run organization with origins dating back to 1968. This year we celebrate 50 years of Passion Innovation. Click to view a historical timeline of BioTek s milestones since entering the life science market.PartnersAs a prospective partner, BioTek can help you achieve your sales and market penetration by providing a unique blend of products, service, support, training, co-marketing and quality assurance designed to meet your customers requirements while you remain focused on your core business.TekTalk NewsletterReview past issues of TekTalk, BioTek s complimentary life science instrumentation e-newsletter. If you are not currently subscribed, you maysign up nowto begin receiving issues as they are released. Our current distribution is 6 issues/year.BlogVisit our blog, Scientifically Speaking, to read what our scientists and instrument experts have to share.CareersAt BioTek we feel passionately and genuinely that our employees are our greatest asset. We continue to build our already impressive team having doubled our global workforce in the last five years. With our headquarters in the beautiful Green Mountains of Vermont, USA, we also have regional offices around the world.If you re interested in becoming part of our amazing team, check out our list of job openings today!Quality ComplianceBioTek is committed to maintaining the high quality of our products and services. All of our products are designed and manufactured in the USA at our Headquarters in Winooski, Vermont. Our continual improvement process includes soliciting customer input on quality and product features, and then designing, validating, manufacturing, and testing products to ensure performance and reliability.Contact UsContact BioTek today. Ask a sales or technical question or request service. Click here for BioTek s customer statement on COVID-19 coronavirus.BioTek Instruments, Inc., a part of Agilent Technologies, is a global leader in the development, manufacture and distribution of life science instrumentation, including imaging microscopy, multi-mode detection, liquid handling and automation systems. Our philosophy transcends conventional thinking and challenges the status quo. We develop fresh, original solutions by unifying concepts that often appear to be opposed. It means to shape and reshape. To engineer, build, deliver and support products that best serve the marketplace by providing what you need, when you need it.Think Possible. It s the difference between leading and following. More About Biotek The LogPhase 600 Microbiology Reader introduces a unique class of absorbance microplate reader to research laboratories. It’s the only 4-plate microplate reader specifically engineered, from the ground up, for ONE purpose, measuring microbial growth curves in log phase at OD600 in standard 96-well microplates. The LogPhase 600 has a robust shaking mechanism and outstanding temperature control to guarantee optimal for bacterial growth curve conditions. LogPhase 600 Microbiology Reader:4-Plate Microplate Absorbance Reader for Measuring Microbial Growth The BenchCel Microplate Handler is a fast and simple benchtop microplate storage and handling system that automates common, high-throughput lab workflows. The BenchCel features a high-speed robot, and its modular design provides the flexibility and scalability required to meet the needs of the most diverse laboratory applications. BenchCel Microplate Handler BioTek’s Cytation Cell Imaging Multi-Mode Readers are the most advanced microplate readers on the market, delivering performance, versatility and reliability in a unique, patented design. Cytation Cell Imaging Multi-Mode Plate Readers: Ready for Any Assay LogPhase 600 Microbiology Reader:4-Plate Microplate Absorbance Reader for Measuring Microbial Growth The LogPhase 600 Microbiology Reader introduces a unique class of absorbance microplate reader to research laboratories. It’s the only 4-plate microplate reader specifically engineered, from the ground up, for ONE purpose, measuring microbial growth curves in log phase at OD600 in standard 96-well microplates. The LogPhase 600 has a robust shaking mechanism and outstanding temperature control to guarantee optimal for bacterial growth curve conditions. The BenchCel Microplate Handler is a fast and simple benchtop microplate storage and handling system that automates common, high-throughput lab workflows. The BenchCel features a high-speed robot, and its modular design provides the flexibility and scalability required to meet the needs of the most diverse laboratory applications. BioTek’s Cytation Cell Imaging Multi-Mode Readers are the most advanced microplate readers on the market, delivering performance, versatility and reliability in a unique, patented design. Designed for measuring microbial growth curves in up to four standard 96-well microplates at a time. Learn More New Agilent BenchCel Microplate Handler!Automate your assay workflow with BenchCel Microplate Handler.BenchCel integrates with several BioTek washers, dispensers, microplate readers and imagers, enabling a wide range of automated workflows. Learn More Synergy H1’s Continuously Variable Bandwidth Monochromators Optimize Assay Performance July 02, 2020 BioTek Instruments announces the availability of variable bandwidth monochromators on their modular and versatile Synergy™ H1 Hybrid Multi-Mode Reader. This allows researchers to achieve even greater levels of assay sensitivity and specificity compared to fixed bandwidth systems. Read more LogPhase 600 Microbiology Reader Measures Microbial Growth Curves in Multiple Microplates June 09, 2020 BioTek unveils a unique class of microplate readers with the new LogPhase 600 Microbiology Reader. The LogPhase 600 is the only four-plate microplate reader purpose-built to perform microbial growth curve analysis. Multiple plate measurements increase throughput and reduce the need for multiple costly single-plate absorbance readers that take up valuable bench space. At the same time, highly consistent environmental conditions support high quality absorbance results without growth curve artifacts, even in bacterial and yeast assays with extended incubation periods. Read more Agilent’s BenchCel Microplate Handler Now Available through BioTek for Full Workflow Automation May 28, 2020 BioTek announces that Agilent’s BenchCel Microplate Handler is now added to its portfolio of walkaway automated solutions. The modular BenchCel Microplate Handler is a high-speed robot with an open, flexible and scalable format to bring efficiency to diverse applications such as ELISA, endpoint add-and-read assays and cell fix-stain-image processes. Read more BioTek Introduces New Cell Count & Viability Starter Kit April 01, 2020 BioTek Instruments today introduced a new kit that can help researchers quickly obtain high-quality cell count results by automating the often tedious and error-prone process of mammalian cell counting. Read more In Vitro Assays for Antiviral Drug Development (COVID-19) March 13, 2020 Researchers around the globe are working to find viable antiviral drugs against COVID-19. There are myriad research methods in use for discovery and development, including in vitro assays in microplates. To help researchers find the best instrumentation for their research, BioTek’s team in China has made recommendations for instrumentation that can be used at several stages of discovery and for several specific in vitro assays. Read more BioTek Announces the New Cytation 7 with Upright and Inverted Microscopes, Plus Multi-Mode Detection January 02, 2020 The new Cytation™ 7 Cell Imaging Multi-Mode Reader from BioTek Instruments combines an automated upright microscope, an inverted microscope, and multi-mode microplate detection in a single instrument. This combination of microscopes and multi-mode reading enables applications that would typically require multiple instruments. Read more BioTek Launches a Set of Quantitative Assay Apps to Simplify Detection-Based Applications October 31, 2019 The new Quantitative Assay Apps from BioTek Instruments, Inc. provide convenience and simplicity for researchers performing four commonly used detection-based applications: absorbance-based BCA, Bradford, Lowry protein assays, and fluorescence-based DNA assays. These easy-to-use Apps are powered through Gen5™ Data Analysis Software and are compatible with BioTek microplate readers equipped with the relevant detection mode, including the popular Cytation™ and Synergy™ multi-mode readers. Read more Agilent Completes Acquisition of BioTek Instruments - Builds on Multi-Year Growth Strategy in Critical Cell Analysis Technology August 26, 2019 SANTA CLARA, CA - Agilent Technologies Inc. (NYSE: A) today announced it has completed the acquisition of BioTek Instruments, a global leader in the design, manufacture and distribution of innovative life science instrumentation. Read more BioTek Recognized as 2019 ‘Vermont Business Growth Award’ Winner August 12, 2019 BioTek Instruments will be recognized as a 2019 Vermont Business Growth Award winner at a ceremony to be held September 17, 2019 at the Hilton Hotel Burlington, in Burlington, VT. This award is presented annually by Vermont Business Magazine and KeyBank, acknowledging twenty-five Vermont businesses that have experienced the greatest growth over the past five years. Read more Agilent to Acquire BioTek, Strengthening Leadership Position in Growing Cell Analysis Segment July 11, 2019 SANTA CLARA, CA. Agilent Technologies Inc. (NYSE: A) today announced it has signed a definitive agreement to acquire privately-owned BioTek Instruments for $1.165 billion. With anticipated tax benefits for Agilent, the net purchase price is expected to be approximately $1.05 billion. Read more BioTek Unveils Enhancements to Market-Leading 405 TS Washer July 01, 2019 BioTek Instruments continues to improve laboratory workflows while simplifying the user experience with the launch of their next generation 405 TS Microplate Washer. With new capabilities, 405 TS provides even more time-saving convenience and value for applications such as cell-based assays, ELISAs, bead washing and more. Read more BioTek Earns Cisbio HTRF Certification June 26, 2019 BioTek’s Synergy™ Neo2 Hybrid Multi-Mode Microplate Reader received expanded certification from Cisbio Bioassays for their proprietary HTRF® technology, a TR-FRET assay platform used in the Life Sciences. Synergy™ Neo2 was recently updated with an optional TRF laser. The TRF laser provides ultra-fast measurement speed, along with optimal sensitivity for critical screening applications like Time-Resolved Fluorescence (TRF) and Time-Resolved Fluorescence Energy Transfer (TR-FRET) assays. Synergy Neo2 now offers HTRF certification with both its flash lamp and laser excitation modes and is an ideal solution for high throughput screening (HTS) and core labs facilitating ultra-fast processing of high-throughput biochemical and cell-based assay workflows. Read more Synergy and Cytation Readers Validated for Agilent MitoXpress and pH-Xtra Assays June 18, 2019 BioTek is pleased to announce that its Synergy™ H1 and Synergy Neo2 Hybrid Multi-Mode Readers and its Cytation™ 1 and Cytation 5 Cell Imaging Multi-Mode Readers are validated for use with the MitoXpress and pH-Xtra Assays from Agilent Technologies. The assays may be used alone or combined to measure metabolism in live cells. Instructional Applications Bulletins are available for each multi-mode reader detailing the specific parameters for optimized TRF performance with MitoXpress Xtra Oxygen Consumption, MitoXpress Intracellular Oxygen and pH-Xtra Glycolysis products. Read more New Scratch Assay Starter Kit Brings Convenience and Reproducibility to Scratch Wound Healing and Invasion Assays June 14, 2019 BioTek Instruments continues to enhance cell biology workflows with the introduction of the Scratch Assay Starter Kit for use with their Lionheart™ Automated Cell Imagers and Cytation™ Cell Imaging Multi-Mode Readers. The Scratch Assay Starter Kit includes the AutoScratch™ Wound Making Tool, Scratch App software, sample packages of 24- and 96-well microplates, and cleaning reagents. Read more BioTek Announces New Wide Field of View Camera for Cytation™ 5 May 23, 2019 BioTek Instruments announces a new wide field of view (FOV) camera option for their Cytation 5 Cell Imaging Multi-Mode Reader. The new wide FOV camera captures approximately four times the area compared to Cytation 5’s standard camera, allowing users to capture larger areas of interest with fewer images. The new camera increases the speed of acquisition for larger samples and accelerates statistically significant sampling for cell population analysis. Read more BioTek instrumentation will be on display by BioTek Europe. Read more BioTek instrumentation will be on display by BioTek U.K. Read more BioTek instrumentation will be on display by BioTek Germany. Read more BioTek instrumentation will be on display by BioTek Europe. Read more BioTek instrumentation will be on display by BioTek U.K. Read more BioTek instrumentation will be on display by BioTek France. Read more BioTek instrumentation will be on display by BioTek Switzerland. Read more BioTek instrumentation will be on display by BioTek Germany. Read more Society for Neuroscience 2020 Washington, DC, United States October 24, 2020 BioTek instrumentation will be on display by BioTek U.S. Read more BioTek instrumentation will be on display by BioTek Taiwan. Read more BioTek instrumentation will be on display by BioTek Germany. Read more BioTek instrumentation will be on display by BioTek U.S. Read more AACR 2021 Washington D.C., United States April 09, 2021 BioTek instrumentation will be on display by Agilent Technologies. Read more Techniques for Improving Cell Culture Quality Control and Assay Optimization-On Demand June 17, 2020 Variability in cell culture characteristics negatively impacts downstream applications, contributing to misleading data and poor assay reproducibility. Conventional methods for evaluating cell culturing techniques and assay optimization consist of manual inspection of a small subset of the cell population at random locations and time points—relying on subjective measurements and processes that are difficult to standardize. In this webinar we will describe methods for improving the quality and reproducibility of cell-based assays using automated imaging tools and liquid handling procedures. Read more Using Automated Imaging to Quantitatively Analyze the Colony Formation Assay - On Demand May 27, 2020 In this webinar, we discuss automated methods for conducting and analyzing the colony formation assay using both the colorimetric and fluorescent properties of crystal violet, the well-established dye for this assay. We will cover important considerations for setting up the colony formation assay in multi-well formats, as well as discuss approaches for constructing a quantitative image analysis workflow that reliably identify colonies and extract meaningful results. Read more Understanding the Enemy: An Applied Review of SARS-CoV-2 and COVID-19 May 13, 2020 This webinar reviews the broad range of research techniques and assay formats employed to develop effective treatments and advance clinical testing. Content covers general virology applications, cellular host response studies, animal models of infection, and therapeutic development. Read more Ask a Scientist Webinar Series for Kids April 30, 2020 Just because your kids are out of school, doesn’t mean the learning has to slow down! 4 of BioTek’s Ph.D-trained scientists are teaching weekly science classes complete with experiments and projects you can do at home. Content is targeted for 7-12 year olds, but all are welcome. Read more 3D Culture Methods and Imaging Considerations - On Demand April 29, 2020 The use of three‐dimensional (3D) culture models is rapidly expanding due to their recognition as representing more structurally and physiologically relevant models of in vivo biology. 3D cell culture assays attempt to mimic the cellular microenvironment including in vivo extracellular matrix (ECM) composition. In this webinar we will cover the advantages and limitations of the various culture models, assay formats, and imaging approaches. Attendees should gain knowledge on setting up and optimizing a broad range of 3D assays that are the best fit for their particular application. Topics Covered: 3D culture models, scaffold free vs. hydrogel matrix models, overview of the generation and use of organoids, molecular, biochemical and imaging assay methods. Read more Tools and Techniques for Optimizing Cell Proliferation Studies - On Demand April 15, 2020 In this webinar we provide a detailed review of available methods for measuring cell proliferation, with a particular focus on recent assay innovations, including both 2D and 3D formats. This information will assist researchers in selecting the most appropriate and effective system for measuring cell proliferation based on a broad range of factors. Additionally, we cover important considerations for setting up and running cell proliferation assays, including techniques for improving the accuracy and reproducibility of results. Read more Advances in Quantitative Image-Based Applications Utilizing a Powerful and Unique Combination of Imaging Tools - On Demand March 25, 2020 BioTek’s Cytation Cell Imaging Multi-Mode Readers are the most advanced microplate readers on the market, delivering performance, versatility and reliability in a unique, patented design. With the recent release of the Cytation 7 and the available upright microscopy module, we’ve further expanded the range of supported applications.In this webinar we described workflows and tips for optimizing a range of recently developed assays, emphasizing integrated automation for increased efficiency and accurate quantitative analysis. Read more Advances in Live Cell Imaging Applications: Quantifying real time cellular responses from seconds to weeks November 13, 2019 Cellular behavior is complex and dynamic. While end-point assays provide a single snapshot of this behavior, it is only when live cells are continually monitored that a more complete understanding of this behavior is realized. At issue, however, is the duration of these dynamics which can occur over seconds, as in the case of intracellular calcium signaling; or continuously, such as the proliferation of a population of cells. Read more Biomolecular and Cellular Quantification Using a Multi-Mode Microplate Reader - On Demand September 25, 2019 Quantification of purified nucleic acids and protein is a preliminary step for a multitude of downstream applications in a wide range of scientific fields of study. Depending on the sample and application, there is a need for a range of methods to best quantify the biomolecule of interest. Here we will discuss the various methods available to accurately and precisely determine a wide range of analyte concentrations typically found during purification. Methods will include the use of micro-volume, microplate and standard one-centimeter path length vessels using a range of detection methods available in microplate readers. Read more A fully automated solution for conducting cell migration assays using the AutoScratch Wound Making Tool - On Demand June 19, 2019 In this webinar we will demonstrate a fully automated cell migration assay using the AutoScratch Wound Making Tool, which provides a convenient and reproducible method for quantifying 2D cellular migration in either 24- or 96-well formats. Additionally, we will present tips and tricks for optimizing scratch assays, including sample preparation, post scratch washing procedures, and techniques for ensuring accurate and meaningful quantitative results. Read more Zebrafish Imaging with Quantitative Analysis - On Demand March 20, 2019 Zebrafish are a powerful vertebrate model for many avenues of biological research including developmental biology and pathology. Due to their small size and optical clarity they are uniquely amendable to imaging studies. In this webinar we will describe how automated digital microscopy and quantitative image analysis can be applied to zebrafish research focusing on three common areas of study including angiogenesis, toxicology and cell death. Read more Image Analysis 101 - Case Studies in Microbiology - On Demand November 7, 2018 In this webinar, we’ll describe how automated digital microscopy methods and high content image analysis tools frequently used in mammalian cell studies are applied to an array of microbial cell models common to bacteriology, virology, mycology, and mixed cell type co-cultures. Using live and fixed microorganisms, and a variety of stains, fluorescent probes and a label-free technique to demonstrate how downstream qualitative and quantitative data outcomes, such as cell counting and unit volume conversion, metabolic activity, strain differentiation, and morphology characterization, are obtained for each of a group of individual case studies. Our goal is to provide tips and insights that can be broadly applied in microbial imaging applications beyond the examples shown. Read more Automated Media Exchanges for Long Term 3D Spheroid Assays Using MultiFlo FX's new AMX Module - On Demand September 19, 2018 Three dimensional (3D) spheroidal cell models have become a mainstay in life science research to provide the most in vivo-like environment. Performing media exchanges and washes with unattached spheroids can be problematic due to the risk of accidental spheroid removal. In this webinar we will introduce the MultiFlo™ FX's new AMX™ Automated Media Exchange Module, a novel automated, peristaltic pump-based tool that allows these procedures to be carried out in a controlled and consistent manner that eliminates spheroid disruption and removal, simplifying long-term 3D experimental procedures. Read more DNA Quantification - Multi-Volume/Multi-Mode Analytical Methods - On Demand March 14, 2018 Nucleic acids are the building blocks of life in all living things, from plants and animals to bacteria and viruses. In research, it’s important to quantify nucleic acids prior to downstream processes like sequencing, restriction enzyme digestions and ligations, PCR and qPCR along with many other applications. Along with determining nucleic acid concentrations, it’s also important to calculate the ratio of nucleic acid to protein to ascertain the purity of the nucleic acid before using the sample in subsequent analyses. Read more Quantitative Intracellular and Intranuclear Spot Analysis Using Digital Microscopy - On Demand November 29, 2017 Phenotypic cellular analysis is a critical area of biological research. Numerous applications require quantifying the number of “spots” per cell, including DNA damage, autophagosomes, endosomes, and mitochondria. These evaluations are often done by hand, which is highly subjective and can be tedious. In this webinar we will describe using an automated image based approach for rapid, objective quantification of various assays that use object spot counting analysis including autophagy, mitochondria membrane potential, genotoxicity, and others. Read more ELISA: Best Practices and Troubleshooting - On Demand September 20, 2017 Enzyme-linked immunosorbent assay (ELISA) is an antibody-based reaction that allows the detection and quantitation of numerous analytes with the same basic assay process. The reaction uses a solid surface, typically a microplate, to immobilize the analyte. Once immobilized, unwanted materials can be removed by washing and the remaining analyte quantitated. The assay technology uses antibodies in conjunction with enzyme-catalyzed amplification to provide high specificity and high sensitivity. Here we will describe the basic process steps of ELISA, best laboratory practices along with troubleshooting tips for common problems. In addition, some of the devices and instrumentation used with this assay technology will be described. Read more Combining Automated Liquid Handling, Cellular Microscopy and Magnetic Bioprinting to Create Walk Away 3D Oncology, Stem Cell Differentiation, and Toxicity Procedures - On Demand May 24, 2017 The use of cells cultured into a three-dimensional (3D) configuration continues to gain acceptance within multiple areas of life science research and drug discovery. Assay procedures commonly performed with two-dimensional (2D) cultured cells are rapidly migrating to 3D because of the reestablishment of cell-cell and cell-extracellular matrix (ECM) interactions, and in vivo-like results these cell models afford. Examples include cell migration studies, stem cell differentiation, and toxicity assessments. Read more Kinetic Proliferation Assay Using High Contrast Brightfield Imaging March 15, 2017 Characterizing cell proliferation is a crucial aspect of biological research and therapeutic drug development. Most current cell proliferation assays rely on indirect biochemical metrics that are limited by artifacts or imaging-based endpoint measures. In this webinar, we will describe a continuous live-cell assay for determining cell proliferation profiles using high contrast brightfield imaging. This fully automated method enables long-term quantitative analysis of cell growth using non-invasive methods to directly count cells or assess % confluence. Read more Enabling Quantitative Cellular Imaging - On Demand November 29, 2016 The science of cell biology relies heavily on microscopy to visualize structure and function of cells. Qualitative assessments can be made with traditional microscopes that rely on oculars to visualize cells and how they behave in homeostasis or under stress. To quantify these processes, it is necessary to digitize images so processing and analysis routines can be employed. Read more Automated Live Cell Imaging - On Demand May 26, 2016 BioTek's Lionheart™ FX Automated Live Cell Imager simplifies live cell imaging by providing a fully integrated solution. While the sample environment is effectively controlled to maintain cell health, all optical components are kept in separate conditions optimal for high resolution microscopy. The Lionheart FX also possesses versatile software allowing the easy creation of time-lapse movies and powerful image analysis enabling quantitative phenotypic assays. These capabilities will be demonstrated in the webinar by several applications including perfusion and wound healing assays. Read more Automated Imaging and Analysis of Genotoxicity using Single Cell Gel/Comet Assay - On Demand March 17, 2016 In this webinar we will demonstrate imaging and analysis procedures using the CometAssay® from Trevigen®. Following staining, automated imaging of each well is performed using the Cytation cell imaging multi-mode reader. Built in Gen5 software, used for analysis and instrument control, then carries out commonly accepted calculations; such as % DNA in the comet tail and tail moment. The combined process can then be used to generate automated, high throughput comet-based genotoxicity data. Read more BioTek Instruments, Inc., headquartered in Winooski, VT, USA, is a worldwide leader in the design, manufacture, and distribution of innovative life science instrumentation. These products enable life science research by providing high performance, cost-effective analysis and quantification of biomolecules, biomolecular interactions and cellular structure and function across diverse applications. BioTek espouses a "Think Possible" approach that sets the tone for fresh ideas, unsurpassed customer service and original innovations. Copyright BioTek Instruments, Inc. 2020 Phone: (888) 451-5171 Contact Us

TAGS:BioTek Instruments biotekinstrumentation lifescienceinstrumentation detection li

<<< Thank you for your visit >>>

BioTek Instruments, Inc. is a global leader in the development, manufacture and sale of life science instrumentation, including imaging & microscopy, multi-mode detection, liquid handling and automation systems.

Hot Websites