Home Page: American Journal of Ophthalmology

Time 2020-09-16 14:04:21

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Full-text articles are available from 1910 to the present. Access to abstracts is complimentary. Access to full text is limited to print subscribers. Register or login to: Buy a Subscription Now Activate Online Access Attention AAO Members Did you know you get electronic access to the AJO through your AAO membership? Click here to login. 5-Year Impact Factor: 4.451View More on Journal Insights 2019 Journal Citation Report Clarivate Analytics, 2020Prognostic Utility of Whole-Genome Sequencing and Polymerase Chain Reaction Tests of Ocular Fluids in Postprocedural EndophthalmitisThe presence and higher load of bacteria other than S epidermidis detected by WGS or DNA from TTV by qPCR in ocular fluids is associated with worse outcomes in post-procedure endophthalmitis.Ten-Year Incidence of Cataract Surgery in Urban Southern China: The Liwan Eye StudyApproximately 1 in 10 participants >50 years of age underwent cataract surgery over 10 years. The incidence was lower than that reported in developed countries, suggesting a substantial unmet demand even in a major urban city in China.Young Adults With Anterior Ischemic Optic Neuropathy: A Multicenter Optic Disc Drusen StudyMost of these young NA-AION patients had ODD. This indicates that ODD may be an independent risk factor for the development of NA-AION, at least in younger patients. The study suggests that ODD-AION be recognized as a novel diagnosis.Descemet Membrane Endothelial Keratoplasty: Ten-Year Graft Survival and Clinical OutcomesMost eyes that underwent surgery in the pioneering phase of DMEK showed excellent and stable clinical outcomes with low postoperative complication rates and primising graft longevitiy over the first decade after surgery. This suggests that DMEK may be a safe long-term treatment option for corneal endothelial diseases.Lacrimal Gland Hamartoma (Formerly Termed Dacryoadenoma)Our study confirms that a subset of isolated epibulbar lacrimal gland lesions differ morphologically and immunohistochemically from normal lacrimal gland tissue and the lacrimal gland in a choristoma. These differences range from subtle to overt, suggesting that isolated epibulbar lacrimal gland lesions may have originated from precursor cellular elements indiginous to the conjunctival (hamartia) and grew into disorganized lacrimal gland tissue.Choroidal Anatomic Alterations After Photodynamic Therapy for Chronic Central Serous Choroidopathy: A Multicenter StjdyAfter PDT for chronic CSCR we observed sustained reductions in CMT and SFCT, while reductions in GCA and LCA were only noted at the 1-month follow-up interval. These choroidal parameters may provide additional quantitative biomarkers to evaluate the anatomic response to therapy but await further prospective validation.Outcomes After Müller Muscle Conjunctival Resection Versus External Levator Advancement in Severe Involutional BlepharoptosisMMCR ptosis repair is an effective approach in treating patients with severe ptosis, and it may offer superior outcomes to ELR. In patients with good responses to phenylephrine, MMCR may offer an efficient and highly efficacious surgery regardless of presenting MRD1.Epidemiology and Clinical Characteristics of Episcleritis and scleritis in Olmsted County, MinnesotaThe Olmsted County, Minnesota, population had a lower incidence of episcleritis and a higher incidence of scleritis than populations in previous studies. The population-based results from this study may provide information that is more applicable to a primary eye care setting.Age-related Macular Degeneration: Nutrition, Genes and Deep Learning - The LXXVI Edward Jackson Memorial LectureCounseling individuals affected with AMD regarding the use of the AREDS2 supplements and the beneficial association of the Mediterranean diet is an important public health message. Although genetic testing is important in research, it is not recommended for prediction of disease or to guide therapies and/or dietary interventions in AMD. Techniques in deep learning hold great promise, but further prospective research is required to validate the use of this technique to provide improvement in accuracy and sensitivity/specificity in clinical research and medical management of patients with AMD. Comment on: “Is this a 737 Max Moment for Brolucizumab”Marcia Kayath, Dirk SauerDOI: https://doi.org/10.1016/j.ajo.2020.06.035Publication stage: In Press Corrected ProofAmerican Journal of OphthalmologyPreviewFull-Text HTMLPDFxWe read with interest the editorial titled “Is this a 737 Max Moment for Brolucizumab.”1 At Novartis, providing safe and effective treatments for patients is our highest priority. Working closely with health authorities around the world, including FDA, we continuously monitor the benefit-risk profile of our medicines. Although other anti–vascular endothelial growth factor (anti-VEGF) agents are available, there are current unmet needs with neovascular AMD (nAMD) treatment that we believe brolucizumab addresses.Comment on “Foveal Crack Sign: An Optical Coherence Tomography Sign Preceding Macular Hole After Vitrectomy for Rhegmatogenous Retinal Detachment”Alessandro Arrigo, Alessandro Marchese, Luisa Pierro, Francesco BandelloDOI: https://doi.org/10.1016/j.ajo.2020.06.037Publication stage: In Press Corrected ProofAmerican Journal of OphthalmologyPreviewFull-Text HTMLPDFxWe read with great interest the recently published article entitled “Foveal Crack Sign: An Optical Coherence Tomography Sign Preceding Macular Hole After Vitrectomy for Rhegmatogenous Retinal Detachment.”1 In this study, Ishibashi and associates assessed the relatioship between thisparticular structural optical coherence tomography (OCT) alteration, namely, a vertical hyperreflective intraretinal foveal line, and the onset and progression of macular holes (MHs).Revising the diagnosis of idiopathic uveitis by peripheral blood transcriptomicsJames T. Rosenbaum, Christina A. Harrington, Robert P. Searles, Suzanne S. Fei, Amr Zaki, Sruthi Arepalli, Michael A. Paley, Lynn M. Hassman, Albert T. Vitale, Christopher D. Conrady, Puthyda Keath, Claire Mitchell, Lindsey Watson, Stephen R. Planck, Tammy M. Martin, Dongseok ChoiDOI: https://doi.org/10.1016/j.ajo.2020.09.012Publication stage: In Press Journal Pre-ProofAmerican Journal of OphthalmologyPreviewFull-Text HTMLPDFxTo test the hypothesis that idiopathic uveitis can be categorized into subtypes based on gene expression from blood.Sex Differences in Academic Rank, Scholarly Productivity, NIH Funding, and Industry Ties Among US Academic Cornea SpecialistsMckenzee Chiam, Mona L. Camacci, Erik B. Lehman, Michael C. Chen, Gargi K. Vora, Seth M. PantanelliDOI: https://doi.org/10.1016/j.ajo.2020.09.011Publication stage: In Press Journal Pre-ProofAmerican Journal of OphthalmologyPreviewFull-Text HTMLPDFxThis study analyzed sex differences among cornea specialists with regards to academic rank, scholarly productivity, National Institute of Health (NIH) funding, and industry partnerships. Design: Cross-sectional study.Incidence and Natural History of Retinochoroidal Neovascularization in Enhanced S-Cone SyndromeSawsan R. Nowilaty, Abrar K. Alsalamah, Moustafa S. Magliyah, Abdulelah A. Alabdullah, Khabir Ahmad, Valmore A. Semidey, Marco Mura, Patrik SchatzDOI: https://doi.org/10.1016/j.ajo.2020.09.010Publication stage: In Press Journal Pre-ProofAmerican Journal of OphthalmologyOpen AccessPreviewFull-Text HTMLPDFSupplemental MaterialsxTo examine the incidence and natural history of macular retinochoroidal neovascularization (RCN) in Enhanced S-Cone Syndrome (ESCS). Influence of artificial tears on keratometric measurements in cataract patientsVeronika Röggla, Christina Leydolt, Daniel Schartmüller, Luca Schwarzenbacher, Elias Meyer, Claudette Abela-Formanek, Rupert MenapaceDOI: https://doi.org/10.1016/j.ajo.2020.08.024Publication stage: In Press Journal Pre-ProofPublished online: August 20, 2020Open AccessFull-Text HTMLPDFDigital Screen Time During COVID-19 Pandemic: Risk for a Further Myopia Boom?Chee Wai WONG, Andrew TSAI, Jost B. Jonas, Kyoko Ohno-Matsui, James CHEN, Marcus ANG, Daniel Shu Wei TINGDOI: https://doi.org/10.1016/j.ajo.2020.07.034Publication stage: In Press Journal Pre-ProofPublished online: July 29, 2020Full-Text HTMLPDFSupplemental MaterialsEffect of Refractive Astigmatism on All-Distance Visual Acuity in Eyes with a Trifocal Intraocular LensKen Hayashi, Motoaki Yoshida, Chizuka Igarashi, Akira HirataDOI: https://doi.org/10.1016/j.ajo.2020.07.051Publication stage: In Press Journal Pre-ProofPublished online: August 7, 2020Open AccessFull-Text HTMLPDFSupplemental MaterialsAppropriate Use and Reporting of Uncontrolled Case Series in the Medical LiteratureJohn H. KempenDOI: https://doi.org/10.1016/j.ajo.2010.08.047Vol. 151, Issue 1Published in issue: January 2011Full-Text HTMLPDFWhat Does Telemedicine Mean for the Care of Patients With Glaucoma in the Age of COVID-19?Richard K. Parrish II, Eve J. HigginbothamDOI: https://doi.org/10.1016/j.ajo.2020.07.038Publication stage: In Press Corrected ProofPublished online: August 12, 2020Full-Text HTMLPDF Access this journal on ScienceDirect Visit ScienceDirect to see if you have access via your institution. An International Journal Click here for a geographic visualization of primary corresponding authors and AJO readers in the last five years.The online-only open access companion journal to the AJO exclusively devoted to the publication of case reports, case series and brief reports.Publications in AJO Case Reports are:Open access and freely available to all readersRapidly available online via Science DirectPeer reviewed by an experienced editorial board Thank You The Journal thanks all of the reviewers who reviewed manuscripts in 2019. A complete list of reviewer names is available here.

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