The Lancet | The best science for better lives

Time 2020-06-17 23:02:57

Web Name: The Lancet | The best science for better lives

WebSite: http://www.thelancet.com

ID:3529

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Journals View articles of the highest standard and extending to all aspects of human health Specialties View collections of articles, reviews, seminars and comments from across our journals Clinic View selected content around 136 diseases according to clinical practice needs Global Health View selected content to advance health in all regions of the world Paediatric brain tumours often have distinctive features from those of adult brain tumours. Because the paediatric brain is more susceptible to the toxic effects of the several therapies these children are exposed to, imaging plays a crucial part in the clinic for an accurate treatment planning, and survival and functioning assessments. Insulin signalling is essential for brain health, and people with diabetes are at increased risk of cognitive impairment and dementia. The prevention and treatment of diabetes could therefore reduce the incidence of cognitive impairment. A joint Series between The Lancet Neurology and The Lancet Diabetes & Endocrinology covers current advances on diabetes and brain health, aiming to shed light on the complex interplay between the central nervous system and peripheral insulin regulation, on screening and prognostication of people at risk of cognitive dysfunction, on early diagnosis, and novel therapeutic approaches, particularly in relation to type-2 diabetes. Cancer kills more than 100,000 children each year, and yet 80% of paediatric cancers are curable with currently available interventions. Notably, the majority of these deaths occur in low‐income and middle-income countries where children have poor access to health services. It is crucial that as countries transition to universal health care, childhood cancers are recognised as a priority for inclusion in benefits packages. Yet no reliable data are available in low-income and middle-income countries on the current and future burden of childhood cancer; on cost of effective interventions; on current coverage levels for diagnostic, treatment, and care services; or on the cost, feasibility, or health and economic benefits of scaling-up effective coverage. There is an imperative for a comprehensive study to estimate the number of new cases, survival with and without treatment, the number of deaths without additional investments to scale up health services and treatment for children with cancer, and to develop an investment framework to establish an evidence-based case for investing in effective interventions to address childhood cancer.  In a new Commission from The Lancet Oncology, Rifat Atun, Carlos Rodriguez-Galindo, and colleagues provide a comprehensive analysis to develop an investment case for funding management and control of childhood cancer. The health and wellbeing of children now and in the future depends on overcoming new challenges that are escalating at such speed as to threaten the progress and successes of the past two decades in child health. The climate emergency is rapidly undermining the future survival of all species, and the likelihood of a world in which all children enjoy their right to health appears increasingly out of reach. A second existential threat that is more insidious has emerged: predatory commercial exploitation that is encouraging harmful and addictive activities that are extremely deleterious to young people’s health. Highest standards for medical science The Lancet sets extremely high standards. We select only the best research papers for their quality of work and the progression they bring. Improving lives in the only end goal Too much research is done for research sake. We believe that improving lives is the only end goal and that research is only relevant when it has an impact on human lives. Increasing the social impact of science We recognise that a great research paper is not enough and that it requires development, mobilisation, and exposure. So we promise to set agendas, create context, inform leaders, start debates, and advocate for the idea that research can and will make a difference.

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